2013
DOI: 10.3109/14767058.2013.845157
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Depression during pregnancy: a risk factor for adverse neonatal outcomes? A critical review of the literature

Abstract: Objective We reviewed studies of maternal depression and preterm birth (PTB), low birthweight (LBW) and small-for-gestational-age (SGA) in the context of methodological differences between studies and potential limitations. Methods We conducted a literature search of PubMed (1996–2011) for English-language studies of maternal depression and (1) PTB and gestational age (GA), (2) LBW and birthweight (BW) and (3) SGA. Thirty-six studies met eligibility criteria. Results Elevated depression levels, particularl… Show more

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Cited by 141 publications
(101 citation statements)
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“…Other perinatal complications arising from mild to clinically relevant symptoms of prenatal maternal stress, depression or anxiety can include premature delivery and low birth weight of the child [118][119][120]. There were also indications that depression in the mother can predispose to intrauterine growth retardation [121][122]. If maternal mental health problems remain untreated, there is a risk that these symptoms will continue even after the birth of the child [123][124], which can seriously limit the maternal care given to the infant and the interaction between mother and infant [125][126][127].…”
Section: Effects Of Stress Depression and Anxiety In Pregnancymentioning
confidence: 99%
“…Other perinatal complications arising from mild to clinically relevant symptoms of prenatal maternal stress, depression or anxiety can include premature delivery and low birth weight of the child [118][119][120]. There were also indications that depression in the mother can predispose to intrauterine growth retardation [121][122]. If maternal mental health problems remain untreated, there is a risk that these symptoms will continue even after the birth of the child [123][124], which can seriously limit the maternal care given to the infant and the interaction between mother and infant [125][126][127].…”
Section: Effects Of Stress Depression and Anxiety In Pregnancymentioning
confidence: 99%
“…Research suggests that maternal depression during pregnancy may be in an important risk factor for LBW and SGA; thus, maternal depressive symptomatology was included as a covariate. 33,34 Data analysis Preliminary analyses examined sociodemographic variables and key study variables to assess distribution of data, and to identify potential outliers and collinearity among variables. T-tests and chi-square analyses were used for continuous and categorical variables respectively.…”
Section: Possible Correlates Of Adverse Neonatal Outcomesmentioning
confidence: 99%
“…There are inconsistent reports in the literature as to depression and its infl uence on preterm birth. A recent critical review of the literature does suggest that depression during pregnancy is a risk factor for preterm birth and smallfor-gestational age [ 30 ]. However, it is diffi cult to tease out the infl uence of depression when factors such as drugs, alcohol, and smoking are frequently associated with depression [ 31 -33 ].…”
Section: Maternal Risk Factors For Spontaneous Preterm Labor and Pprommentioning
confidence: 99%