In recent years, depression in university students has been of growing concern. This especially attracted attentions among research degree students due to higher levels of stress they faced; Master's and PhD students have been reported the highest suicide rates in comparation to undergraduate students. Psychological counselling that provided by psychology teachers in colleges thus became significantly important to these students. As such, this research study aims at analysing depression levels in college students, through an intercultural perspective focusing on how college psychology teachers were motivated to support these students. This article starts with an introduction to the research background, followed by a review of literature on the definitions of depression, psychology teacher motivation, and intercultural perspectives. Furthermore, the article explains how psychology teacher motivation plays role in college students depression from an intercultural perspective. This article concludes by a brief summary of the study and emerging recommendations.