Depression in Epilepsy: A Common but Often Unrecognized Comorbid Malady

Kanner, Andrés M.; Palac, Susan

doi:10.1006/ebeh.2000.0030

Cited by 152 publications

(90 citation statements)

References 86 publications

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“…Neurologists do not routinely screen PWE for depression, 50 Consequently, depression is under recognized and untreated in PWE, 13 In our study 32% of the preoperatory group and 21% of the pos-operatory group had symptoms of depression. From this group only 32% of the pre-operatory group and 69% of the pos-operatory group was taking antidepressants.…”

Section: Discussionmentioning

confidence: 53%

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Screening symptoms of depression and suicidal ideation in people with epilepsy using the Beck depression inventory

Salgado

Nogueira

Yasuda

et al. 2012

J. epilepsy clin. neurophysiol.

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Objective: To measure the severity of symptoms of depression and suicidal ideation in people with epilepsy (PWE) before and after epilepsy surgery using the Beck Depression Inventory (BDI). We aimed to determine the factors associated to depression in PWE. Methods: PWE, regardless of epilepsy type, seizure type, duration or frequency of seizures, and AEDs were investigated. The sample (n=468) was divided into two groups: preoperatory (n=346) and pos-operatory (n=122). Results: Before epilepsy surgery female gender, unemployment and high seizure frequency were associated factors for the occurrence of symptoms of depression. After epilepsy surgery, the only factor associated to high level of depression symptoms was the lack of seizure remission. Suicidal ideation was associated to seizure frequency before and after epilepsy surgery. Conclusion: Our results confirm the generally held view that depression is common in PWE and provide further insight to the association of depression with certain socio-demographic and seizure-related factors before and after epilepsy surgery.Keywords: epilepsy, seizures, depression, suicidal ideation. RESUMO Rastreamento de sintomas de depressão e ideação suicida em pessoas com epilepsia usando o inventário de depressão de BeckObjetivo: Avaliar a gravidade dos sintomas de depressão e ideação suicida em pessoas com epilepsia (PCE), antes e após o tratamento cirúrgico utilizando o Inventário de Depressão de Beck (BDI). Nosso objetivo foi determinar os fatores associados à depressão em PCE. Métodos: PCE, independentemente do tipo de epilepsia, tipo de crises, duração ou frequência das crises, e DAEs, foram investigados. Os pacientes (n=468) foram divididos em dois grupos: pré-operatório (n=346) e de pós-operatório (n=122). Resultados: Antes do tratamento cirúrgico, o sexo feminino, o desemprego e a alta frequência de crises foram fatores associados à ocorrência de sintomas de depressão. Após a cirurgia de epilepsia, o único fator associado ao alto nível de sintomas de depressão foi a falta de remissão de crises. Ideação suicida foi associada à frequência de crises antes e após a cirurgia de epilepsia. Conclusão: Nossos resultados confirmam a opinião generalizada de que a depressão é comum nas PCE e proporcionam mais evidência para a associação de depressão com alguns fatores sócio demográficos e relacionados às crises antes e após o tratamento cirúrgico das epilepsias.Unitermos: epilepsia, crises epilépticas, depressão, ideação suicida.

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Section: Discussionmentioning

confidence: 53%

“…11,12 Unfortunately, most PWE are not regularly screened for depression and consequently, are not treated. 13 There may be many reasons to explain why depression goes unrecognized in PWE. One of these is the lack of efficient screening measures with well established sensitivity and specificity.…”

Section: Introductionmentioning

confidence: 99%

Screening symptoms of depression and suicidal ideation in people with epilepsy using the Beck depression inventory

Salgado

Nogueira

Yasuda

et al. 2012

J. epilepsy clin. neurophysiol.

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“…[42] Levetirasetam, zonisamid, topiramat ve tiagabin ile de benzer bildirimler mevcuttur. [43][44][45][46] …”

Section: Risk Faktörleriunclassified

Psychiatric Disorders in Children and Adolescents with Epilepsy

Ekinci¹,

Toros²

2013

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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ÖZETEpilepsi yüksek morbiditeye sahip kronik bir hastalıktır. Son yıllarda yapılmış çok sayıda araştırma epilepsi tanılı çocuk ve ergenlerde ruhsal bozuklukların sık olarak görüldüğünü göstermiştir. En sık görülen ruhsal bozukluklar arasında depresyon, anksiyete bozuklukları ve dikkat eksikliği hiperaktivite bozukluğu yer almaktadır. Aralarında demografik değişkenler, epilepsi ile ilişkili nedenler ve psikososyal faktörler olmak üzere çok sayıda faktörün epilepside ruhsal bozuklukların gelişiminde rol oynadığı düşünülmektedir. Ruhsal bozukluk eş tanılarına yaklaşımda disiplinler arası işbirliği, hasta ve ailenin eği-timi ve psikososyal destek büyük önem taşımaktadır. Araştırmalar bazı psikotrop ilaçların epilepsi tanılı çocuk ve ergenlerde genel olarak yüksek bir güvenilirlik ve etkinlikle kullanılabileceğini göstermiştir. Anahtar Sözcükler: Epilepsi, çocuk, ergen, ruhsal bozukluk ABSTRACTEpilepsy is a chronic disease with a high morbidity. Many recent studies have shown that psychiatric disorders are commonly encountered in children and adolescents with epilepsy. Depression, anxiety disorders and attention deficit hyperactivity disorder are among the most common psychiatric disorders. Many factors, including demographic variables, epilepsy related factors and psychosocial factors, have been suggested to have a role on the development of psychiatric disorders in epilepsy. In the management of psychiatric comorbidities, cooperation between disciplines, education of the patient and family and psychosocial support are of vital importance. Recent studies have shown that some psychotropic agents can be used with a generally high safety and efficacy in children and adolescents with epilepsy.

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“…The risk for psychiatric disorders in people with epilepsy have been reported to be three to six times higher than observed in age matched apparently healthy population [1,15,18]. It has also been documented that children and adolescents with epilepsy experience more emotional and behavioural problems than healthy controls and others with chronic conditions [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

“…Both epilepsy and depression are characterized by a chronic course and poor long-term psychosocial outcome [2]. Authors have identified psychiatric syndromes such as anxiety, depression, and behavioural affective and conversion disorders in people with epilepsy [8][9][10][11][12][13][14][15][16][17][18]. The risk for psychiatric disorders in people with epilepsy have been reported to be three to six times higher than observed in age matched apparently healthy population [1,15,18].…”

Section: Introductionmentioning

confidence: 99%