Depression in <scp>P</scp>arkinson's disease: the effectiveness and risk of pharmacotherapy. Clinical review

Dyduch, Agnieszka; Załuska, M

doi:10.1111/psyg.12078

Cited by 9 publications

(7 citation statements)

References 58 publications

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“…Despite the high prevalence of depression in PD, only 10-20% of sufferers receive treatment, which is typically anti-depressant treatment and may have limited efficacy for PD patients (Dyduch and Załuska, 2015;Frisina et al, 2008). In a meta-analysis that included randomized placebo controlled treatments for depression and anxiety in PD, we found a non-significant moderate effect size for anti-depressants (d = .71) and a significant large effect size (d = 1.57) for cognitive behaviour therapy (CBT) (Troeung et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Modified Mindfulness-Based Cognitive Therapy for Depressive Symptoms in Parkinson's Disease: a Pilot Trial

Rodgers

Schütze

Gasson

et al. 2019

Behav. Cogn. Psychother.

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Background: Mindfulness-based cognitive therapy (MBCT) has evidence of efficacy in a range of populations, but few studies to date have reported on MBCT for treatment of anxious and depressive symptoms in Parkinson's disease (PD). Aims: The aim of this study was to examine the efficacy of modified MBCT in reducing symptoms of anxiety and depression and improving quality of life in PD. Method: Thirty-six individuals with PD were randomly assigned to either modified MBCT or a waitlist control. Changes in symptoms of anxiety, depression and quality of life were compared at group level using generalized linear mixed models and at individual level using reliable change analysis. Results: At post-treatment, there was a significant reduction in depressive symptoms for people undertaking modified MBCT at both group and individual levels compared with controls. There was no significant effect on anxiety or quality of life at the group level, although significantly more people had reliable improvement in anxiety after modified MBCT than after waitlist. Significantly more waitlist participants had reliable deterioration in symptoms of anxiety and depression than those completing modified MBCT. Most participants stayed engaged in modified MBCT, with only three drop-outs. Discussion: This proof-of-concept study demonstrates the potential efficacy of modified MBCT as a treatment for depressive symptoms in Parkinson's disease and suggests further research is warranted.

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Section: Introductionmentioning

confidence: 99%

Modified Mindfulness-Based Cognitive Therapy for Depressive Symptoms in Parkinson's Disease: a Pilot Trial

Rodgers

Schütze

Gasson

et al. 2019

Behav. Cogn. Psychother.

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“…There are four core symptoms in PD: tremor at rest, rigidity, bradykinesia (slowness), and postural instability. However, more of other motor-symptoms, such as freezing and dyskinesia also observed among PwP at different stages of the disease (Dyduch & Załuska, 2014;Jankovic, 2008;Lim, Fox, & Lang, 2009;Politis, Wu, Mollis, Bain, Chaudhuri & Piccini, 2010). The non-motor symptoms are such as constipation, pain, sleep disorders, cognitive impairments, poor memory, slowness in psychological responses, problems of visuospatial functioning (Aarsland, Larsen, Karlsen, Lim, & Tandberg, 1999;Jenkinson, Peto, Fitzpatrick, Greenhall, & Hyman, 1995;Meireles & Massano, 2012;Pagonabarraga, Kulisevsky, Strafella, & Krack, 2015), and sensory motor integration impairments (Clark, Adams, Dykstra, Moodie, & Jog, 2014;Jankovic, 2008;Ramig, Fox, & Sapir, 2007;Richardson, Sussman, Stathopoulos, & Huber, 2014).…”

Section: Introductionmentioning

confidence: 97%

Voice Characteristics of People with Parkinson’s Disease (PwP): An Overview on Baseline Vocal Characteristics and Guidelines for Therapeutic Singing

Ang

2018

MJM

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Parkinson's Disease (PD) is a chronic neurodegenerative disease in which the symptoms of the disease are worsen over time. Core symptoms of the disease are such as tremor-at-rest, rigidity, postural instability, and bradykinesia. Apart from these motor-problems, other problems such as sleep disorder, sensory abnormalities, neuropsychiatric disorders also exist. In addition to the motor-problems, latest literature documented 80-90% of the people with Parkinson's Disease (PwP) are prone to develop voice impairment known as Parkinsonian Dysarthria, when symptoms deteriorate, causing loss of communication, difficulties in swallowing and breathing that are psychologically devastating and life threatening. Growing research in music therapy (MT) and music-based rehabilitative activities worldwide documented positive effects on PwP. A local research using therapeutic singing as rehabilitative model at the Malaysian Parkinson's Disease Association (MPDA) also have reported positive benefits in improving vocal problems in the Malaysian PwP. In this research, some primary and preliminary data on the vocal characteristic, including baseline vocal loudness (VL), pitch range (PR) and respiratory rate (RR) were obtained among 22 local PwP prior to examining effects of singing on PwP. Findings of this study showed that the PwP speak softer than the normal accepted range. The findings also showed that they have tendency to develop rapid breathing, and their average pitch range while singing is limited within the range of G#3 -B4. These findings can further propose guidelines for voice rehabilitation models based on the preliminary voice characteristics concluded in this study.

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“…Depression is often emphasized as a major factor in determining the quality of life. However, despite its impact, there was very limited attention being paid to this matter, nor was it being treated in clinical practice (Chung et al, 2003;Dyduch & Załuska, 2014;Rahman et al, 2008;Shulman et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…Non-motor problems co-exist with the motor dysfunction, and can be manifested intricately in many different ways. So it is an important factor to determine the quality of life which can modify the course of PD (Dyduch & Załuska, 2014).…”

Section: Introductionmentioning

confidence: 99%

Exploring the Reception of the Tele-Based Music Program in People with Parkinson’s Disease During the Period of the Movement Control Order Due to The Covid-19 Pandemic

Foong¹,

Selvarajah²

2021

IJARBSS

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One of the consequences of the Covid-19 pandemic was the country's lockdown with the new normal "social-distancing" being mandated. This might have worsened the management of some chronic diseases such as Parkinson's Disease (PD). PD is a chronic neurodegenerative disease in which the symptoms of the disease worsen over time. Apart from the prominent motor problems, studies also noted that the quality of life (QoL) of the People with Parkinson's Disease (PwP) deteriorates significantly with increasing disease severity. The impairment in the QoL often causes PwP to social withdrawal and social isolation, leading to higher possibilities for PwP to develop neuropsychiatric disorders such as anxiety and depression, as well as causing caregivers' distress. A tele-based music program was designed for the PwP aiming to encourage social engagement and to instil positive living. This paper reports the preliminary findings of the reception of a trial tele-based music program on psychosocial wellbeing in people with PwP.

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Depression in Parkinson's disease: the effectiveness and risk of pharmacotherapy. Clinical review

Cited by 9 publications

References 58 publications

Modified Mindfulness-Based Cognitive Therapy for Depressive Symptoms in Parkinson's Disease: a Pilot Trial

Modified Mindfulness-Based Cognitive Therapy for Depressive Symptoms in Parkinson's Disease: a Pilot Trial

Voice Characteristics of People with Parkinson’s Disease (PwP): An Overview on Baseline Vocal Characteristics and Guidelines for Therapeutic Singing

Exploring the Reception of the Tele-Based Music Program in People with Parkinson’s Disease During the Period of the Movement Control Order Due to The Covid-19 Pandemic

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