Depression of nerve-mediated smooth muscle contractions in vitro by plasma of an anephric rabbit and uremic patients.

Abstract

Isolated hypogastric nerve

Bilateral Nephrectomy Delays Gastric Emptying of a Liquid Meal in Awake Rats

“…It is conceivable that one of the several nitrogen compounds that accumulate in the extracellular fluid could inhibit the contractility of the gastrointestinal smooth muscle. [22] Another possibility is that bilateral nephrectomy induces hemodynamic changes that could interfere with the gastrointestinal motor behavior. As a matter of fact, we have shown that acute hypervolemia, due to saline or blood infusion, increased the resistance offered by the gastroduodenal segment to the flow of liquid and delayed the gastric emptying of liquid in rats.…”