Depth profile of diffuse reflectance near‐infrared spectroscopy for measurement of water content in skin

Arimoto, Hidenobu; Egawa, Mariko; Yamada, Yukio

doi:10.1111/j.1600-0846.2005.00093.x

Cited by 95 publications

(73 citation statements)

References 15 publications

(15 reference statements)

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“…However, the beam path length in media is highly influenced by wavelength since optical properties such as scattering and absorption coefficients and anisotropy parameters are the functions of wavelength. Previous studies 33 have concluded that the water bands at 1450 and 1900 nm visible in skin spectra have different absorption coefficients, and, therefore, have a different measurement depth. The water band around 1900 nm was shown to have a higher absorption coefficient, resulting in a shorter measurement in comparison to the band near 1450 nm since photons lose their energy more rapidly in the spectra range of strong water absorption.…”

Section: Resultsmentioning

confidence: 99%

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Qassem

Kyriacou

2014

J. Biomed. Opt

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Citation: Qassem, M. & Kyriacou, P. A. (2014). Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function. Journal of Biomedical Optics, 19(8), 087007. doi: 10.1117/1. JBO.19.8.087007 This is the accepted version of the paper.This version of the publication may differ from the final published version. Abstract. A number of noninvasive techniques and instruments have emerged over the years allowing much progress toward clarifying the structure and function of human skin and studying the effects of various applied substances. All of this research has provided great insight into the interactions between skin and various products through quantitative and qualitative measurements. Such methods include near-infrared spectroscopy (NIRS), a technique which has gained popularity over the years and has often been employed to accurately determine the moisture levels and water content of skin based on its sensitivity to hydrogen bonding. NIRS has also been applied in many studies to report the efficacy of moisturizing products and assess their benefits to the skin. However, many of these studies have reported an increase in skin water content following moisturizer application while some have challenged the benefits of long-term moisturizer use, particularly on normal skin, and even suggested that it can increase the skin's susceptibility to irritants. This paper reports the results of a pilot in vivo study carried out on the skin of 20 healthy volunteers, categorized into groups depending on their skin type and frequency of moisturizer use, in order to investigate the optical response of human skin after direct short-term contact with water followed by application of a moisturizer. The measurements were obtained using a highly advanced spectrophotometer in the region of 900 to 2100 nm equipped with a customized reflectance fiber optic handheld probe. Scatter graphs of group results and second derivative spectra have shown an interesting pattern between frequent users of moisturizers and individuals who do not use moisturizers, suggesting that long-term daily moisturization may have an effect on skin barrier function. The results also raise some questions regarding the optical characteristics of different skin types, as well as the varying response between different water bands in the NIR region. Future work will focus on gaining more knowledge about these subjects and obtaining results from a larger population, as well as performing statistical analysis through regression methods in order to further improve optical skin measurements. Permanent

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Section: Resultsmentioning

confidence: 99%

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Qassem

Kyriacou

2014

J. Biomed. Opt

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“…The interrogation volume of these probes is defined in part by the spacing between the source and detector fibers. 37 Fiber-probe-based methods enable interrogation of ex vivo and in vivo intact tissues because, unlike integrating sphere setups, these methods typically employ measurement geometries that can be approximated as semi-infinite by radiative transport modeling approaches and thus do not require concurrent reflectance and transmittance measurements or an a priori knowledge of sample thickness. These fiber-based systems can also be employed preclinically or clinically due to their portable, flexible, and minimally invasive nature.…”

Section: Introductionmentioning

confidence: 99%

Review of short-wave infrared spectroscopy and imaging methods for biological tissue characterization

et al. 2015

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“…13 Many studies have investigated the sampling depth in scattering media both experimentally and numerically. [12][13][14][15][16] Most of these studies rely on the diffusion approximation, which is not valid for short SDSs and highly absorbing media. Others investigated the sampling depth only for reflectance probes with specific geometries, such as single-fiber reflectance, 16 overlapping illumination and collection areas, 17,18 large SDSs (SDS > 1∕μ 0 s ), 19 and diffuse reflectance spectroscopy probes only at specific SDSs and fiber diameters.…”

Section: Introductionmentioning

confidence: 99%

“…The light penetration depth depends not only on the absorption and scattering properties of the tissue, but also on the geometry of the diffuse reflectance probe. 12 Because of this, the depth sampling of a DRS probe can be tuned by adjusting the probe geometry, allowing for the design of application specific probes. 13 Many studies have investigated the sampling depth in scattering media both experimentally and numerically.…”

Section: Introductionmentioning

confidence: 99%

Effect of probe geometry and optical properties on the sampling depth for diffuse reflectance spectroscopy

et al. 2014

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Abstract. The sampling depth of light for diffuse reflectance spectroscopy is analyzed both experimentally and computationally. A Monte Carlo (MC) model was used to investigate the effect of optical properties and probe geometry on sampling depth. MC model estimates of sampling depth show an excellent agreement with experimental measurements over a wide range of optical properties and probe geometries. The MC data are used to define a mathematical expression for sampling depth that is expressed in terms of optical properties and probe geometry parameters. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Depth profile of diffuse reflectance near‐infrared spectroscopy for measurement of water content in skin

Abstract: The correlations between the water contents measured by the optical and capacitance techniques were discussed. The dependencies of the light penetration depth on the source-detector geometry and wavelength are presented.

Cited by 95 publications

References 15 publications

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function

Review of short-wave infrared spectroscopy and imaging methods for biological tissue characterization

Effect of probe geometry and optical properties on the sampling depth for diffuse reflectance spectroscopy

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