Der Aktionsplan zur Verbesserung der Arzneimitteltherapiesicherheit (AMTS)

Sommer, Herbert; Dwenger, Anne

doi:10.1016/j.zefq.2012.10.020

Cited by 3 publications

(1 citation statement)

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“…First regulatory steps have been taken in Germany with the Action Plan for the Improvement of Drug Therapy Safety [20]. However, over-the-counter medication would presumably not be recorded using this method, although it may be possible that pharmacies could add this information for medications purchased there.…”

Section: Discussionmentioning

confidence: 99%

Potential Interactions of Medication Prescribed in Discharge Letters from a Clinic for Hematology and Oncology

Schaefer¹,

Keinki²,

Osthoff³

et al. 2018

Oncol Res Treat

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Background: As there are few data worldwide concerning the frequency and relevance of interactions of prescribed drugs in hemato-oncology, we analyzed the medication prescribed to patients at a clinic within a comprehensive cancer center. Methods: Details of the medication prescribed for all patients in 2011 were extracted from their discharge letters. All potential medication combinations were assess with respect to the risk of interaction using 3 specialized websites. Results: The files of 202 patients receiving 275 drugs were extracted; 4,303 drug combinations were created. Overall, 88% of these combinations were found to be harmless with an interaction value (IV) of 1. However 10% showed potential risk of probable interaction (IV 2 + 3). 47% of the patients had at least 1 drug combination with a risk of interaction. A maximum of 29 drugs with 15 probable and possible interactions were found. Conclusion: Awareness for this topic should be raised in physicians and patients. An important step for avoiding risks of interactions is a systematic check of all drugs prescribed. There is urgent need for reliable data on clinically relevant interactions and for a better network in which physicians and pharmacists can exchange data about relevant interactions.

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Section: Discussionmentioning

confidence: 99%