Scheminzky (see Scheminzky, 1940Scheminzky, , 1947, and the papers quoted therein) has shown that constant currents flowing longitudinally along the vertebral column of frogs can evoke muscular inhibition (Galvanonarkose) if the cathode is situated caudally, and muscular spasm (galvanischer Krampf) if it is cephalic. Evidence exists that the phenomenon is of central origin (Kollensperger & Scheminzky, 1938), and the interpretation has been suggested (Scheminzky, 1940) Baumgarten (1949) has shown that when current flows between two electrodes placed at the two opposite ends of the vertebral column of frogs, opposite motor effects can be obtained not only by reversing the polarity of the electrodes but also simply by displacing the trunk of the sciatic nerve. From these results he infers that Scheminzky's effect is conditioned by the electrotonic polarization of peripheral nerves.In the present research, part of which has been previously reported (Ajmone Marsan, Fuortes & Marossero, 1949b), an approach to the interpretation of Scheminzky's phenomenon was attempted by studying the actions of galvanic currents on the rhythmical activity of the spinal grey matter of mammals.