Derivatives of glutamic acid as new surfactants>

Abstract

Starting from glutamic acid, different types of surfactants have been synthesised by using original trimodular strategies. Monosubstituted zwitterionic amides of glutamic acid obtained with excellent yields show good surface activity. The grafting of a second hydrophobic side-chain leads to bicatenar cationic surfactants or to disubstituted nonionic cyclic compounds. In order to reduce the hydrophobic character of the bicatenar surfactants, a second synthetic method has been developed, allowing the introduction of a polar sugar group into these molecules. The surfactant properties of several of the products have been determined by physico-chemical methods such as surface tension measurements and compression isotherm studies by means of a Langmuir balance.

Genotoxicity potentials of anionic and cationic amino acid-based surfactants

“…Dodecylamine (99%) from were obtained Sigma-Aldrich (Istanbul, Turkey) l -Glutamic acid (99%) were from Fluka (Istanbul, Turkey) and dodecanol were (99%) from Merck (Istanbul, Turkey). The synthesis of molecules 1 and 2 (Figure 2) was carried out according to Rodehüser et al (2000).…”

Comparative studies of interactions of hemoglobin with single-chain and with gemini surfactants

“…n-Dodecylammonium α-glutamate (GDA) was synthesized and purified according to the method of Ref. [24] and a detailed synthesis of glutamic acid-based gemini surfactants (L 2 G 2 C n ) is seen in the supporting materials. Water used was distilled twice.…”

Aggregation behavior of an amino acid-derived bolaamphiphile and a conventional surfactant mixed system

“…All other reagents used were of analytical grade from Shanghai Chemical Reagent Company, and ultrapure Millipore water (18.2 MX) was used as solvent. [27]. L-Histidine (1.552 g, 10 mmol) and a suspension of 1,12-diaminododecane (1.002 g, 5 mmol) in 50 mL of water were introduced into a flask equipped with a magnetic stirred bar.…”