Dermatitis-producing Anacardiaceae of the Caribbean area

Lampe, Kenneth F.

doi:10.1016/0738-081x(86)90076-3

Cited by 17 publications

(6 citation statements)

References 26 publications

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“…Although the mango fruit is sometimes considered to be nonallergenic even by plant taxonomists, there are many records of dermatological problems . Such incidences appear to be less frequent in tropical areas where the fruit is grown, and it has been suggested that eating mango in infancy and steadily thereafter may result in oral desensitization . The fruit peel seems to be the chief source of mango dermatitis, and circumoral dermatitis is frequent if the fruit is eaten without removal of the skin , .…”

Section: Introductionmentioning

confidence: 99%

“…Such incidences appear to be less frequent in tropical areas where the fruit is grown, and it has been suggested that eating mango in infancy and steadily thereafter may result in oral desensitization . The fruit peel seems to be the chief source of mango dermatitis, and circumoral dermatitis is frequent if the fruit is eaten without removal of the skin , . Epicutaneous tests on human subjects with fruit peel and isolated pentadecyl-, heptadecenyl-, and heptadecadienylresorcinols elicited strong positive reactions and pointed out that allergenicity of these compounds, which was found to be IgE mediated, depends on the degree of unsaturation in the alkyl chain .…”

Section: Introductionmentioning

confidence: 99%

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Quantitative Determination of Allergenic 5-Alk(en)ylresorcinols in Mango (Mangifera indica L.) Peel, Pulp, and Fruit Products by High-Performance Liquid Chromatography

Knödler

Reisenhauer

Schieber

et al. 2009

J. Agric. Food Chem.

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Despite a number of serious case reports of mango dermatitis, no attempts at the identification and quantification of allergenic 5-alk(en)ylresorcinols in mango fruits have so far been made. Therefore, total alk(en)ylresorcinol content and relative homologue composition in 13 mango peel samples and 7 samples of mango pulp were determined by HPLC and LC-MS/MS analyses. Furthermore, mango puree and nectar prepared on pilot plant scale were also analyzed and compared with commercially available thermally preserved products. Depending on cultivar, alk(en)ylresorcinol contents ranged from 79.3 to 1850.5 mg/kg of dry matter (DM) in mango peels and from 4.9 to 187.3 mg/kg of DM in samples of mango pulp. The profile of alk(en)ylresorcinols was found to be highly characteristic, with an average homologue composition of C15:0 (6.1%), C15:1 (1.7%), C17:0 (1.1%), C17:1 (52.5%), C17:2 (33.4%), C17:3 (2.4%), C19:1 (2.1%), and C19:2 (0.8%). Mango puree samples prepared from peeled and unpeeled fruits revealed contents of 3.8 and 12.3 mg/kg of fresh weight, respectively. Content and homologue composition were not significantly affected during puree processing and thermal preservation. In nectar samples prepared from peeled and unpeeled fruits, contents of 1.4 and 4.6 mg/L, respectively, were found.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quantitative Determination of Allergenic 5-Alk(en)ylresorcinols in Mango (Mangifera indica L.) Peel, Pulp, and Fruit Products by High-Performance Liquid Chromatography

Knödler

Reisenhauer

Schieber

et al. 2009

J. Agric. Food Chem.

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“…In case of mango ingestion, patients developed lesions consistent either with localised contact dermatitis (perioral skin lesions associated with occasional lip and facial edema), or with disseminated dermatitis (patients displaying skin lesions in areas that were not in contact with the fruit) [35,38,42]. It was previously thought that perioral lesions can develop if the fruit is eaten whole, without removal of the skin, thus the fruit could be enjoyed if peeled by another person [43]. However, Weinstein et al had shown that the 5 mm of flesh under the skin contains enough sensitising compounds to induce dermatitis in sensitised patients [34].…”

Section: Discussionmentioning

confidence: 99%

Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

et al. 2021

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Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: We reviewed the original articles published on Pubmed, Embase and Cochrane Library before 15 September 2021, on the topic of contact allergy induced by mango and we synthesized the key data. Results: We found 12 case reports and four case series, with a total of 37 patients. Only seven of these cases were reported in patients from mango-cultivating countries, the other 30 were from countries where mango cultivation does not occur, and 26 were also from countries where poison ivy/oak are commonly found. We found that contact dermatitis may occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants. The diagnosis was confirmed by patch testing in some of the cases. There was great heterogeneity between the reagents used. Conclusion: Mango fruit is frequently consumed, but mango induced contact dermatitis, the main hypersensitivity reaction induced by mango, is rare. Further data is necessary for a better understanding of sensitising substances and, consecutively, standardization of patch test reagents.

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“…Allergenic Anacardiaceae [43][44][45][46][47] The cashew nut tree (Anacardium occidentale) grows worldwide in the tropics. The nuts contain an oily, brown juice between the two layers of the shell.…”

Section: Anacardiaceae 23738mentioning

confidence: 99%