Dermatomiofibromas múltiples

Multiple dermatomyofibromas

“…Multiple dermatomyofibromas are extremely rare, with few reports worldwide. 2 In this case, besides the rarity of the condition, the multiple lesions made the diagnosis difficult, requiring in depth studies in order to make the distinction between other fibroblastic skin entities relevant to the affected site.…”

“…The main features of the tumor are the orientation of the cells, parallel to the surface of the epidermis, the preservation of appendices and absence of mitoses and atypia. 2 , 7 , 8 …”

“…Dermatomyofibroma can also be mistaken by a hypertrophic scar. Some authors say that the differentiation between them can be done by the presence of elastic fibers, that are preserved in dermatomyofibroma 1 , 2 , 6 , 9 and abnormal or absent in hypertrophic scars. 1 - 3 , 6 However, for Ferreira and D'Assumpção, elastic fibers are almost absent in keloids, but can be found in hypertrophic scars, what can make differentiation difficult.…”

“…Dermatomyofibroma is not caused by trauma in the affected area and grows slowly but steadily, as opposed to hypertrophic scar, that appears after an injury and tends to regress spontaneously sometime after the initial trauma. 2 , 9 , 10 Clinically, hypertrophic scars are raised, firm and restricted to the margins of the original lesion, 2 , 10 whereas dermatomyofibroma usually presents as a small lesion, many times more palpable than visible. 2 , 9 …”

“…However, there are reports of larger dermatomyofibromas. 2 , 3 Its coloration can vary from skin-color to red-brown. It occurs preferentially in young women and pre-pubertal children.…”