Dermatoses in 156 Obese Adults

Abstract

TOPETE, JORGE GONZALEZ-BARRANCO, ANTONIO R. VILLA, JOSE J. DALMAN, AND GUADALUPE OR-TIZ-PEDROZA. Dermatoses in 156 obese adults. Obes Res.Background: Skin diseases are mentioned as a frequent finding in the obese patient. However, to our knowledge no study has been done on this subject. Objective: To determine the prevalence of skin diseases associated with different obesity grades and if any dermatosis can be considered an obesity marker. Materials and Methods: A cross-sectional study of 156 obese patients who were 110% to 293% overweight were included. Complete medical history and dermatological examination were done. Results: In the 126 female and 30 male obese patients, grades I to V, with a body mass index (BMI) of 27-51, cutaneous findings with statistical significance for linear trend were: plantar hyperkeratosis 54 patients p = 0.00001 ; acanthosis nigricans 46 patients p = 0.00005; striae 67 patients p = 0.03; skin tags 69 patients p = 0.01; keratosis pilaris 33 patients p = 0.007. Patients with plantar hyperkeratosis were distributed in the obesity groups as follows: grade I = 3 patients; grade I1 = 7 patients; grade I11 = 8 patients; grade IV = 17 patients; and grade V = 19 patients. Of the 76 diabetic patients, 26 had acanthosis nigricans, 38 had skin tags, and 27 had plantar hyperkeratosis. Discussion: Plantar hyperkeratosis should be considered as a cutaneous stigma of severe obesity. This is probably a result of pressure directly related to the excess weight.

Skin - A Mirror Reflecting Underlying Obesity

“…The most common dermatological finding observed in the study was acanthosis nigricans seen in 64.44%, similar to studies by Hud et al [ , 4] Garcia-Hidalgo et al [5] . the incidence of acanthosis nigricans increased with increasing BMI similar to Hud et al , Katz et al [6] and Burke et al [7] studies.…”

Erişkin Obez Hastalarda Dermatolojik Bulgular

“…In our study, the frequency of acrochordon was significantly higher in obese patients, but there was no statistically significant difference between patients with and without insulin resistance. Thus, our results do not support the findings of Kahana et al 19 , but they support the findings of Garcia-Hidalgo et al 10 . In addition, we found that the mean age of patients with acrochordon was higher in both groups, although there was no significant difference.…”

“…The plantar hyperkeratosis may be regarded as a physiologic response to mechanical trauma 9 and hyperkeratosis of the soles in obesity was first described by Garcia-Hidalgo et al in 1999 10 . It was reported that obese patients showed increased forefoot width and higher plantar pressures during standing and walking in study of Hills et al 11 Because of this, we think that plantar hyperkeratosis is an expected finding in obesity.…”

Obezite ile İlişkili Dermatozların Obezlerde ve Aşırı Kilolularda Araştırılması

“…Bir başka çalışmada ise 156 obez hastanın 69'unda akrokordon saptanmış ve VKİ ile akrokordon sayısı iliş-kili bulunmuştur. 15 Çalışmamızda da obez ve aşırı kilolularda kontrol grubuna göre anlamlı olarak daha fazla akrokordon görüldü. Ancak akrokordon varlığını muhtemelen bir derecelendirmeye tabi tutmadığımız-dan aşırı kilolu ve obez grup arasında bir fark tespit edemedik.…”

“…Garcia-Hidalgo ve ark. 15 akantozis nigrikans sıklığını VKİ 27-35 kg/m 2 olan hasta grubunda %14,7-17,9, VKİ 40 ve üzeri olan hastalarda ise %40'ın üzerinde bulmuşlardır. Ayrıca Hud ve ark.…”