Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis

Ito, Takamasa; Natsuga, Ken; Tanimura, Shintaro; Aoyagi, Satoka; Shimizu, Hiroshi

doi:10.2340/00015555-1795

Cited by 20 publications

(31 citation statements)

References 12 publications

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“…Ito et al reported that ill-defined borders, vascular telangiectasia, white projections, and island-like structures surrounding the ulcerous areas are the dermoscopic features of actinic cheilitis. [15] The border regularity with vascular enlargement and proliferation were identified to be the dermoscopic features of plasma cell cheilitis. [15] Dermoscopy of viral warts is characterized by dotted vessels surrounded with white halos.…”

Section: Discussionmentioning

confidence: 99%

“…[15] The border regularity with vascular enlargement and proliferation were identified to be the dermoscopic features of plasma cell cheilitis. [15] Dermoscopy of viral warts is characterized by dotted vessels surrounded with white halos. [16] We suggest that dermoscopic examination can be useful in differential diagnosis of lip SCC which shows peculiar dermoscopic findings mentioned above.…”

Section: Discussionmentioning

confidence: 99%

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Dermoscopic features of lower lip squamous cell carcinoma: A descriptive study

Elmas

Metin

Kilitçi

2019

Indian Dermatol Online J

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Aim:Dermoscopic features of cutaneous squamous cell carcinoma (SCC) have been well described; however, there are a few studies focused on the dermoscopic aspect of lip SCC. In this study, we aimed to identify dermoscopic findings of lower lip SCC.Materials and Methods:The clinical and histopathologic features, dermoscopic images, and demographic data of the patients with histologically approved lip SCC were retrospectively evaluated.Results:A total of 10 lesions were enrolled in the study. Milky red structureless background (100%) and keratin scale (100%) were present in all the lesions. Blood spots on thick keratin scale were observed in eight lesions. Seven lesions showed white structureless areas. Two lesions exhibited ulceration and one of the lesions had structureless brown pigmentation. The most common vascular pattern observed was polymorphous vascular pattern (60%).Conclusion:White and milky red structureless areas, blood spots on thick keratin scale, and polymorphous vascular pattern are the main dermoscopic clues to lip SCC. The presence of these findings should direct the clinician to the possibility of SCC. The dermoscopic findings observed may also reflect histological grade of the lesion.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Dermoscopic features of lower lip squamous cell carcinoma: A descriptive study

Elmas

Metin

Kilitçi

2019

Indian Dermatol Online J

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“…Dermoscopic criteria for AC diagnosis include ill-demarcated lesion borders, white-coloured projections, ‘island’-like structures and radially arranged vascular telangiectasia surrounding ulcerated areas ( 41 ). In the present case report, a milky-white plaque with well-defined borders surrounded by telangiectatic and tortuous vessels was identified in our patient (Case 1).…”

Section: Discussionmentioning

confidence: 99%

Non-invasive imaging of actinic cheilitis and squamous cell carcinoma of the lip

Lupu

Căruntu

et al. 2018

mol clin onc

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An early diagnosis is of overwhelming importance for the management and prognosis of mucocutaneous cancer. Actinic cheilitis (AC), defined by the clonal expansion of genomically unstable keratinocytes, is the most common potentially malignant lesion affecting the lips. Squamous cell carcinoma (SCC) is the most frequent oral malignancy, and there is strong evidence that the majority of the SCCs of the lip originate from AC. There is considerable difficulty in discerning between dysplasia and invasive carcinomas solely on a clinical basis. Although dermoscopy has become an essential tool for skin tumor evaluation, reflectance confocal microscopy (RCM) is a non-invasive imaging technology that has proved itself extremely useful in the diagnosis and monitoring of several skin diseases, including AC and SCC. The present study aimed to re-emphasize the usefulness of RCM in the early detection of malignant transformation, using AC and SCC of the lips as working examples. Due to the apparent innocuousness of AC for numerous patients, it is not possible to overstress the importance of a correct and early diagnosis, proper treatment and long-term patient follow-up as being essential for preventing the progression to lip SCC, or for its timely diagnosis.

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“…Diagnosis and treatment of AC can be challenging; it has been shown that the clinical appearance of AC correlates poorly with the degree of dysplasia (5)(6)(7)(8)(9), thus clinicians have little evidence about the severity of the disease. The accuracy of diagnosis can be increased with new imaging techniques, such as dermoscopy, with the presence in AC of ill-demarcated borders, vascular telangiectasia, white-coloured projections and island-like structures around the ulcerous areas (10), or confocal mi-croscopy (11). Performing a biopsy is mandatory in cases of doubtful lesions.…”

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confidence: 99%

Actinic Cheilitis Prevalence and Risk Factors: A Cross-sectional, Multicentre Study in a Population Aged 45 Years and Over in North-west Spain

Rodríguez-Blanco¹,

Flórez²,

Paredes-Suárez³

et al. 2018

Acta Derm Venerol

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Actinic cheilitis is thought to be a premalignant lesion or a superficial squamous cell carcinoma. The prevalence of actinic cheilitis in Europe is unknown. The aim of this study was to determine the prevalence of actinic cheilitis in the Galicia region (north-west Spain). Secondary objectives were the description of risk factors of actinic cheilitis. A cross-sectional multicentre study in patients ≥ 45 years of age was performed in 8 dermatology departments in Galicia region during a 1-year period. The prevalence of actinic cheilitis was 31.3%. Significant and independent risk factors of actinic cheilitis after multivariate analysis were age ≥ 60 years, Fitzpatrick skin phototype II, outdoor working for more than 25 years, and previous history of non-melanoma skin cancer. This is the first cross-sectional multicentre study of the prevalence of actinic cheilitis in Europe. Actinic cheilitis was present in almost one-third of the screened patients. Lip examination should be performed in all patients with chronic actinic damage.

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Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis

Cited by 20 publications

References 12 publications

Dermoscopic features of lower lip squamous cell carcinoma: A descriptive study

Dermoscopic features of lower lip squamous cell carcinoma: A descriptive study

Non-invasive imaging of actinic cheilitis and squamous cell carcinoma of the lip

Actinic Cheilitis Prevalence and Risk Factors: A Cross-sectional, Multicentre Study in a Population Aged 45 Years and Over in North-west Spain

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