Dermoscopic Findings for the Early Detection of Melanoma: An Analysis of 200 Cases

Ciudad-Blanco, C.; Avilés-Izquierdo, J.A.; Lázaro‐Ochaita, Pablo; Suárez‐Fernández, R.

doi:10.1016/j.adengl.2014.07.015

Cited by 26 publications

(29 citation statements)

References 23 publications

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“…All three dermoscopic variables showed a P-value less than 0.05. Our data confirmed that these were dermoscopic patterns indicative of melanomas [21][22][23][24]. Moreover, we found the presence of blue-white veil in 33.09% of melanomas.…”

Section: Discussionsupporting

confidence: 93%

“…Discordance on the presence/absence of these patterns was only 8.4% (27 dysplastic nevi and nine in-situ melanomas) ( Table 3). The choice of these three parameters was made on the basis of the consideration that blue-white veil, regression and vascular structure polymorphism are dermoscopic parameters that strongly correlate with melanoma [21][22][23][24]. Moreover, in our previous studies such dermoscopic patterns were not well covered by the computer-assisted evaluation.…”

Section: Medical History and Dermoscopic Datamentioning

confidence: 99%

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Computer-assisted melanoma diagnosis

et al. 2015

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In dermatology, attempts at synergy between man and machine have mainly been made to improve melanoma diagnosis. The aim of the present study was to test an 'integrated digital dermoscopy analysis' (i-DDA) system with a series of melanocytic lesions that were benign and malignant in nature, and to evaluate its discriminating power with respect to histological diagnosis. In a retrospective study we used an i-DDA system to evaluate a series of 856 excised, clinically atypical pigmented skin lesions (584 benign and 272 malignant). The system evaluated 48 parameters to be studied as possible discriminant variables, grouped into four categories (geometries, colours, textures and islands of colour) integrated with three personal metadata items (sex, age and site of lesion) and presence/absence of three dermoscopic patterns (regression structures, blue-white veil and polymorphic vascular structures). Stepwise multivariate logistic regression of i-DDA data selected nine variables with the highest possible discriminant power. At the end of the stepwise procedure the percentage of cases correctly classified by i-DDA was 89.2% (100% sensitivity and 40.8% specificity). The limitations of the study included those associated with a retrospective design and the 'a priori' exclusion of nonmelanocytic skin lesions. By incorporating numerical digital features with personal data and some dermoscopic patterns into the learning process, the proposed i-DDA improved the performance of assisted melanoma diagnosis, with the advantage that our results can be objectively repeated in any other clinical setting. Melanoma Res 25:537-542

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Section: Discussionsupporting

confidence: 93%

Section: Medical History and Dermoscopic Datamentioning

confidence: 99%

Computer-assisted melanoma diagnosis

et al. 2015

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“…Noktalar ise globüllerden daha küçük dermoskopik yapılardır ve dermisteki pigmente makrofajları veya epidermisteki tekli ya da küçük agregatlar şeklinde bulunan melanom hücrelerini temsil etmektedir 1 . Melanomların yaklaşık %44'ünde gözlendiği belirtilen düzensiz nokta/globüllerin melanom tanısı için sensitivitesi %75, spesifitesi ise %64 olarak bildirilmekte olup radyal faz ile mikro-invaziv evreyi gösterdiği düşünülmektedir 1,22 . Bizim olgularımızda da benzer şekilde ince, in situ, mitoz oranı <1, LVİ (-), ülserasyon (-) ve regresyon (-) olan melanomlarda düzensiz nokta/globüllerin daha yüksek oranda gözlendiği belirlenmiş, ancak istatistiksel olarak anlamlılık izlenmemiştir.…”

Section: Discussionunclassified

“…Mavi-beyazımsı tül, Ciudad-Blanco ve ark. 22 tarafından daha çok invaziv melanomlarda olmak üzere ortalama %22 oranda gözlenmiştir. Benzer şekilde Silva ve ark.…”

Section: Discussionunclassified

“…Dermoskopik olarak ağ yapısından veya ana kitleden normal deriye doğru uzanan lineer uzantılar ışınsal uzantılar, parmağımsı uzantılar ise psödopodlar olarak adlandırılmaktadır. Histopatolojik olarak her ikisi de bileşke bölgesinde atipik melanositik pagetoid yayılım gösteren melanositik yuvaları temsil etmektedir ve radyal büyüme fazındaki ince melanomlar için karakteristiktir 1,22,23 . İnce melanomlarda yapılan araştırmalarda ışınsal uzantılarin %53,6 oranında, psödopodların ise %4,9 oranında gözlendiği ve ince melanomların invaziv olanlarında in situ olanlara göre daha fazla izlendiği belirtilmiştir 3 .…”

Section: Discussionunclassified

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Investigation of the relationship between dermoscopic features and histopathological prognostic indicators in patients with cutaneous melanoma

Özbağçıvan¹,

Lebe²,

Akarsu³

et al. 2015

TURKDERM

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Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults

Dinnes

Deeks

Chuchu

et al. 2018

Cochrane Database of Systematic Reviews

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Background Early accurate detection of all skin cancer types is important to guide appropriate management, to reduce morbidity and to improve survival. Basal cell carcinoma (BCC) is almost always a localised skin cancer with potential to infiltrate and damage surrounding tissue, whereas a minority of cutaneous squamous cell carcinomas (cSCCs) and invasive melanomas are higher-risk skin cancers with the potential to metastasise and cause death. Dermoscopy has become an important tool to assist specialist clinicians in the diagnosis of melanoma, and is increasingly used in primary-care settings. Dermoscopy is a precision-built handheld illuminated magnifier that allows more detailed examination of the skin down to the level of the superficial dermis. Establishing the value of dermoscopy over and above visual inspection for the diagnosis of BCC or cSCC in primary-and secondary-care settings is critical to understanding its potential contribution to appropriate skin cancer triage, including referral of higher-risk cancers to secondary care, the identification of low-risk skin cancers that might be treated in primary care and to provide reassurance to those with benign skin lesions who can be safely discharged. Objectives To determine the diagnostic accuracy of visual inspection and dermoscopy, alone or in combination, for the detection of (a) BCC and (b) cSCC, in adults. We separated studies according to whether the diagnosis was recorded face-to-face (in person) or based on remote (imagebased) assessment.

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Dermoscopic Findings for the Early Detection of Melanoma: An Analysis of 200 Cases

Abstract: Dermoscopy facilitates the diagnosis of melanoma and could be useful for differentiating between melanoma in situ and invasive melanoma.

Cited by 26 publications

References 23 publications

Computer-assisted melanoma diagnosis

Computer-assisted melanoma diagnosis

Investigation of the relationship between dermoscopic features and histopathological prognostic indicators in patients with cutaneous melanoma

Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults

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