Dermoscopic findings in different clinical variants of lichen planus. Is dermoscopy useful?

Friedman, Paula; Sabban, Emilia Cohen; Marcucci, Carolina; Peralta, Rosario; Cabo, Horacio

doi:10.5826/dpc.0504a13

Cited by 47 publications

(49 citation statements)

References 9 publications

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“…However, epidemiological history, clinical presentation and dermoscopic findings pointed to the diagnosis of LPP, which was confirmed through histopathology [9,10]. …”

Section: Figmentioning

confidence: 99%

Isolated Body Hair Loss: An Unusual Presentation of Lichen Planopilaris

Vendramini

Silveira

Duque‐Estrada

et al. 2016

Skin Appendage Disord

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“…However, epidemiological history, clinical presentation and dermoscopic findings pointed to the diagnosis of LPP, which was confirmed through histopathology [9,10]. …”

Section: Figmentioning

confidence: 99%

Isolated Body Hair Loss: An Unusual Presentation of Lichen Planopilaris

Vendramini

Silveira

Duque‐Estrada

et al. 2016

Skin Appendage Disord

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“…Although its pathogenesis is still unknown, there is evidence that immunological mechanisms, infections, genetic predisposition, allergic reactions to drugs, psychogenic disorders and some chronic and endocrine diseases may play important roles [1,2]. It has been reported that LP shows cancerous characteristics, but its neoplastic transformation rate in skin is low; while oral LP increases the risk of squamous cell carcinoma [3,4], and the World Health Organization (WHO) has classified oral LP as "potentially malignant lesions" [5].…”

Section: Introductionmentioning

confidence: 99%

Expression of YAP in the Skin Lesions of Lichen Planus

Zheng¹

2016

CRDOA

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Objective: To explore the expressions of yes-associated protein (YAP) in skin lesions of lichen planus (LP) and normal skin. Methods:Immunohistochemistry was carried out to quantify the expression of YAP in tissues from the lesions of 30 patients with LP and 30 healthy controls. Results:In normal skin tissues, YAP was slightly expressed in the basal layers of the epidermis, and the positive rate was 26.67% (8/30). In LP, YAP was strongly expressed in the lower layers of the stratum spinosum and some of the infiltrating lymphocytes, and the positive rate was 56.67% (17/30). The expression of YAP in LP was significantly higher than that of normal skin (P < 0.05).Conclusions: YAP may be involved in the occurrence and development of LP.

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“…In cutaneous LP, WS most commonly present as white streaks in a reticular pattern, although other patterns have been reported including circular, radial streaming, linear, globular, veil-like, leaf venation, and starry sky/white dots 10, 13, 14 . In the current case, WS presented as – veil-like structureless grey-white to bluish white areas, and specked-pearly pattern in few foci.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy

Sonthalia¹,

Varma²,

Jha

et al. 2018

F1000Res

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Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham’s striae constituting the hallmark of the condition. However, the dermoscopic features of oral lichen planus with hand-held or videodermoscopy remain to be elucidated. We present the case of a young adult man who presented with asymptomatic white lacy lesions over a bluish-black background over the tongue, patchy hyperpigmentation of the buccal mucosa and gingivae, and longitudinal melanonychia involving some nails. History of intake of any drugs preceding the lesions, smoking, chewing of betel nut and dental implants was negative. Family history was non-contributory. There were no cutaneous lesions suggestive of lichen planus. Mucoscopy (dermoscopy of the mucosa, oral in this case) and onychoscopy were done followed by biopsy from the tongue that confirmed the diagnosis of lichen planus. Oral mucoscopy of the tongue revealed a tri-colored pattern with structureless veil-like grey-white areas (modified Wickham’s striae), well-demarcated red glossy erosions, and violaceous-to-brown clods. Additionally, vascular pattern of dotted and linear to curved vessels along the borders of leukoplakia-like areas and erosions were observed. Onychoscopy confirmed lichen planus-associated melanonychia. Dermoscopy also proved useful in conveniently ruling out other disorders typified by mucosal and nail pigmentation such as Laugier Hunziker syndrome and drug-induced changes. Although direct oral microscopy has been used in defining features of oral lichen planus, to the best of our knowledge this case is the first report on mucoscopy or dermoscopy of oral lichen planus

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Dermoscopic findings in different clinical variants of lichen planus. Is dermoscopy useful?

Cited by 47 publications

References 9 publications

Isolated Body Hair Loss: An Unusual Presentation of Lichen Planopilaris

Isolated Body Hair Loss: An Unusual Presentation of Lichen Planopilaris

Expression of YAP in the Skin Lesions of Lichen Planus

Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy

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