Dermoscopy of acrokeratosis verruciformis of Hopf

Mixed Variant of Acrokeratosis verruciformis of Hopf: A rare entity

“…Dermoscopy of AKV show white homogenous areas, central white network, peripheral cobble stone appearance with typical "Sunray appearance" and regularly arranged brown dots in the non-lesional skin. 10,11 The effective treatment option for AKV is superficial ablation. 3 Other options include topical retinoic acid, cryotherapy or destructive lasers such as CO 2 or Nd:YAG.…”

Acrokeratosis verruciformis of Hopf: dermoscopic and histopathological study of two siblings

“…2 The first description of the dermoscopic features of AVH was in a report of a single sporadic case with Fitzpatrick skin type V. Under nonpolarized contact dermoscopy, the papules featured irregular white homogeneous areas, a white network and a cobblestone appearance. 6 However, in a recently published case, polarized dermoscopy of the acral papules of AVH showed central white homogeneous areas, a central white network, peripheral cobblestone appearance, multiple brown pigmented dots arranged radially in the periphery (sunray appearance), and regularly arranged brown dots with background erythema in the nonlesional skin.…”

“…5 The dermoscopic features of AVH have been described in only two published case reports to date. 6,7 We report two further patients with AVH and describe the dermoscopic features.The patients were a 7-year-old boy and a 5-year-old girl, who were two siblings born to the same…”

“…5 The dermoscopic features of AVH have been described in only two published case reports to date. 6,7 We report two further patients with AVH and describe the dermoscopic features.…”

The Skin in Cowden Syndrome

“…Histologically, both acral keratoses and palmoplantar keratoses show non-specific orthokeratosis, hypergranulosis, and acanthosis ( 8 ). Differential diagnoses of genetic causes of acral keratoses and palmoplantar pits include Buschke-Fischer-Brauer keratoderma ( 29 ), Darier's disease ( 30 – 32 ), Cole disease ( 33 ), and nevoid basal cell carcinoma (Gorlin) syndrome ( 34 – 36 ) ( Table 2 ).…”