Dermoscopy of pigmented papillated Bowen disease: A report of two cases

Namiki, Takeshi; Ichiyama, Susumu; Funasaka, Yoko; Ito, Michiko; Kanzaki, Akiko; Miura, Keiko; Nojima, Kohei; Saeki, Hidehisa; Yokozeki, Hiroo; Tanaka, Masaru

doi:10.1111/1346-8138.13467

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…At present, in some case reports or small studies, RCM has been reported as a diagnostic aid for BD (Ianosi et al, 2019;Lacarrubba et al, 2021;Mazzilli et al, 2020;Namiki et al, 2017;Rstom et al, 2022;Shahriari et al, 2018). According to existing studies, the easily accepted diagnostic points of RCM for BD include irregular honeycomb patterns in the epidermis, atypical cellular structures in the spinous layer, vessels in tortuous morphology inside the dermal papilla, and infiltration of inflammatory cells.…”

Section: Discussionmentioning

confidence: 99%

“…Dermatoscopy can magnify the surface of the skin and observe its submicroscopic structure and pathological changes simply and conveniently (Mazzilli et al, 2020). Researchers have probed into the value of dermatoscopy in diagnosing Bowen's disease, but its diagnostic value is limited since many skin diseases, such as actinic keratosis(AK), psoriasis, melanoma, contact dermatitis, may be similar to Bowen's disease in clinical practice and under dermatoscopy (Namiki et al, 2017;Wozniak-Rito & Rudnicka, 2018).…”

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confidence: 99%

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Application of In Vivo Reflectance Confocal Microscopy in the Diagnosis of Bowen's Disease

Ding,

Hu,

Rao

et al. 2024

Preprint

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Bowen’s disease (BD) is a relatively rare early-stage squamous cell carcinoma in situ, most commonly affecting the middle-aged and elderly, and occurring on the skin or mucous membranes of various parts of the body. Its onset is concealed, the course of the disease is chronic, and some patients are accompanied by malignant tumors outside the skin, so it is necessary to diagnose and evaluate the disease in its early stage. This study aims to investigate the application of reflectance confocal microscopy (RCM) in diagnosing Bowen’s disease. We performed RCM imaging on the lesion site of 113 patients initially diagnosed with Bowen’s disease in clinic, of which 92 patients underwent skin biopsy for histological diagnosis. A retrospective analysis of the RCM result as well as the histological examination revealed that after analyzing RCM images, 69 out of 113 patients were diagnosed with Bowen’s disease; out of 92 biopsy lesions, 61 were Bowen’s disease, of which 54 were consistent with RCM diagnosis. Among 59 cases diagnosed with Bowen’s disease by RCM, 54 cases were consistent with histological diagnosis. Afterwards, we analyzed the RCM characteristics in patients with Bowen’s disease verified by biopsy, and compared the RCM images of two different lesions, Classic Bowen’s Disease (CBD) and Pigmented Bowen’s Disease (PBD), and further summarized the key points of Bowen’s disease under RCM. Finally, we focused on the differential characteristics between Bowen’s disease and other skin diseases under RCM. It is found that RCM is of great value in diagnosing Bowen’s disease.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Application of In Vivo Reflectance Confocal Microscopy in the Diagnosis of Bowen's Disease

Ding,

Hu,

Rao

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Moreover, in this pigmented form, we find an abundance of melanocytes in the epidermis. 1 , 3 , 5 , 7 , 8 The choice of treatment depends on factors such as localization, size and number of lesions as well as the patient's comorbidities. Several option have been described, such as surgical excision, topical 5-fluorouracil, topical imiquimod, cryotherapy, curettage and electrocoagulation, radiotherapy, laser and photodynamic therapy.…”

Section: Introductionmentioning

confidence: 99%

Collision tumor: pigmented Bowen's disease and seborrheic keratosis

Fernandes

Martinez

Nobre

et al. 2018

An. Bras. Dermatol.

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Bowen's disease is a type of squamous cell carcinoma in situ of the skin. The pigmented form is rare and represents less than 2% of cases. We report a case of a 74-year-old black man with a blackened and asymptomatic leg injury for about 6 months. Clinically, and under dermatoscopy, the injury was suggestive of melanoma or melanoacanthoma, and a definitive diagnosis was made by histopathological examination.

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Application of in vivo reflectance confocal microscopy in the diagnosis of Bowen's disease

Ding,

Hu,

Rao

et al. 2024

Microscopy Res & Technique

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Bowen's disease (BD) is a relatively rare early‐stage squamous cell carcinoma in situ, most commonly affecting the middle‐aged and elderly, and occurring on the skin or mucous membranes of various parts of the body. Its onset is concealed, the course of the disease is chronic, and some patients have malignant tumors outside the skin; therefore, it is necessary to diagnose and evaluate the disease at an early stage. This study aimed to investigate the application of reflectance confocal microscopy (RCM) in the diagnosis of BD. We performed RCM imaging on the lesion site and underwent skin biopsy for histological diagnosis of 92 patients initially diagnosed with BD in clinic. A retrospective analysis of the RCM result as well as the histological examination revealed that after analyzing RCM images, out of 92 biopsy lesions, 61 were diagnosed with BD, of which 54 were consistent with RCM diagnosis. Among the 59 cases diagnosed with BD by RCM, 54 cases were consistent with the histological diagnosis. Afterwards, we analyzed the RCM characteristics in patients with BD verified by biopsy, and compared the RCM images of two different lesions, classic Bowen's disease and pigmented Bowen's disease, and further summarized the key points of BD under RCM. Finally, we focused on the differential characteristics between BD and other skin diseases in RCM. RCM is of great value in the diagnosis of BD.Research Highlights A retrospective study of RCM and histological diagnosis in patients with clinical diagnosis of BD. Analyze the RCM characteristics of skin lesions verified by biopsy. RCM is of great value in the diagnosis and differentiation of BD.

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Dermoscopy of pigmented papillated Bowen disease: A report of two cases

Cited by 4 publications

References 5 publications

Application of In Vivo Reflectance Confocal Microscopy in the Diagnosis of Bowen's Disease

Application of In Vivo Reflectance Confocal Microscopy in the Diagnosis of Bowen's Disease

Collision tumor: pigmented Bowen's disease and seborrheic keratosis

Application of in vivo reflectance confocal microscopy in the diagnosis of Bowen's disease

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