Goal of research: creation of an automated complex for quick and effective identification of an unacceptable condition of drivers before going to run and predicting their physiological state during a work shift. To achieve this goal in the creation of devices for the automated complex the following methods were used: photoplethysmographic method, pulse oximetric method, thermometric method. In the course of the research, results were achieved that make it possible to record physiological parameters of drivers with high reliability. This is achieved thanks to the use of the “isobestic point” photoplethysmogram in the registration at a length of 805 nm, the use of a two-channel pulse oximeter at wavelengths of 660 nm and 910 nm.