Description of Ciplukan Toxicity (Physalis angulata L.)

Abstract

As a traditional medicine by people in Indonesia, the parts of the ciplukan plant that are commonly used are the roots, stems, fruit, and leaves. 2 The medicinal power possessed by these plants is related to the content of secondary metabolites, among others, ciplukan leaves are reported to contain saponins, alkaloids, and steroids. The ciplukan stems are reported to contain steroid, alkaloid, saponin, and flavonoid compounds. Ciplukan fruit is reported to contain saponins, alkaloids, and triterpenoids, while ciplukan roots were reported to contain alkaloid group compounds. 10 Results of literature review by Panjaitan et al. 11 showed that the ethanol extract of ciplukan stems contained alkaloid, phenolic, flavonoid, saponin, and terpenoid group compounds. Ciplukan fruit contains alkaloids, saponins, flavonoids, and phenolic compounds, while ciplukan leaves contain flavonoids. Related to activity in medicine, among others, that ciplukan leaves have potential anti-diarrheal activity, 12 antioxidants, 9,13-15 antibacteria, analgesic, 17 and anti-mycobacterium tuberculosis. Ciplukan stems are reported to have potential anti-inflammatory activity, 19 antioxidant, 9 and antihypercholesterolemia. 20 Ciplukan fruit is reported to contain potential antioxidant activity, 9,21 antihypercholesterolemia, 20 and antibacterial. Ciplukan root is also reported to have potential antifungal and antibacterial activity, 23 antiinflammatory, 24 and antibacterial. 25 In addition, from the results of a literature review by Panjaitan et al. 11 it is known that ciplukan has potential as an anti-inflammatory, antioxidant, antidiarrheal, antihypercholesterolemia, and immunomodulator.