Descriptive epidemiology of chordomas in the United States

Das, Paramita; Soni, Pranay; Jones, Jaes; Habboub, Ghaith; Barnholtz‐Sloan, Jill S.; Recinos, Pablo F.; Kshettry, Varun R.

doi:10.1007/s11060-020-03511-x

Cited by 40 publications

(37 citation statements)

References 19 publications

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“…Chordomas are rare, locally aggressive neoplasms of notochordal origin, accounting for 1% to 4% of all bone malignancies and 0.5% of all primary intracranial central nervous system. [4] They characteristically tend to recur. In our case, a 33-year-old woman presented with acute new neurologic symptoms in a scenario of spinal cord metastatic intradural chordoma.…”

Section: Discussionmentioning

confidence: 99%

The role of pelvic rehabilitation in quality of life in a patient harboring metastatic chordoma: a case report

Duarte¹,

Oliveira²,

Vellutini³

et al. 2022

Brazilian Journal of Oncology

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Introduction:Chordoma is a malignant tumor that usually involves the axial skeleton. Intradural chordomas are even rarer and 37 cases have been reported to the best of our knowledge. We present a case of a patient with an atypical metastatic diffuse intradural spinal involvement. Objective: To investigate therapeutic approaches such as pelvic physiotherapy for hospitalized and palliative patients in a private institution diagnosed with advanced cancer. Case Report: We present a 33-year-old woman previously submitted to five brain surgeries to treat a posterior fossa intradural chordoma since December 2012. There were new vertebral intradural lesions. The patient underwent complementary treatment with pelvic physiotherapy to improve the quality of life of the urinary and fecal system. Material and Methods: After six sessions of pelvic physiotherapy in bed and a month of behavioral monitoring and exercise practice, she returned to the condition of adequate urinary continence, thus obtaining an expressiveness in the overall quality of life.

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Section: Discussionmentioning

confidence: 99%

The role of pelvic rehabilitation in quality of life in a patient harboring metastatic chordoma: a case report

Duarte¹,

Oliveira²,

Vellutini³

et al. 2022

Brazilian Journal of Oncology

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“…Axial chordoma is a rare neoplasm with an estimated incidence of less than 0.1 in 100,000 individuals. 19 Extra-axial skeletal and soft tissue chordoma is even rarer, with no apparent predilection for any bone or anatomic site. Herein the clinicopathologic characteristics of all reported cases of brachyury-positive extra-axial chordomas (n ¼ 37, including the current case) are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

Pediatric Extra-Axial Chordoma: Case Report and Literature Review

2021

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Extra-axial chordomas in the pediatric population are extremely rare and diagnostically challenging; only four cases have been previously reported with ages ranging from 13 to 20 years. We report a primary extra-axial chordoma involving the soft tissue directly dorsal and ulnar to proximal phalanx in the right thumb of a 12-year-old girl who presented with worsening right thumb pain for 1.5 years. The diagnosis was confirmed by excisional biopsy demonstrating proliferation of large, polygonal epithelioid cells with diffuse expression of pan-cytokeratin and brachyury. The patient required repeat excision for local recurrence seven months later. Since then, she has remained disease free through 15 months surveillance. Extra-axial chordomas share the same histopathological and immunohistochemical characteristics with their axial counterparts and should be considered in the differential diagnosis for any extra-axial bone or soft tissue mass with epithelioid morphology.

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“…According to the recent descriptive epidemiology in the United States, the age-adjusted incidence rate of all types of chordomas was 0.88 per million persons per year from 2001 to 2014. [ 1 ] The annual age-standardized incidence rate of chordomas in Taiwan from 2003 to 2010 was 0.4 per million, showing male predominance. [ 2 ]…”

Section: Epidemiologyunclassified

Chordoma at the skull base, spine, and sacrum: A pictorial essay

Lee

Kwok

Wong

et al. 2022

JCIS

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Chordomas are rare tumors believed to be arising from the notochord remnant in the axial skeleton. Diagnosis is often difficult since they show overlapping imaging features with other more common disease including metastases. Since individualized papers are only discussing the imaging features at different locations, the aim of this pictorial review is to have a comprehensive review on the common imaging findings of chordomas along the entire neuroaxis with a series of pathological proven cases in a local tertiary hospital in Hong Kong.

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Descriptive epidemiology of chordomas in the United States

Cited by 40 publications

References 19 publications

The role of pelvic rehabilitation in quality of life in a patient harboring metastatic chordoma: a case report

The role of pelvic rehabilitation in quality of life in a patient harboring metastatic chordoma: a case report

Pediatric Extra-Axial Chordoma: Case Report and Literature Review

Chordoma at the skull base, spine, and sacrum: A pictorial essay

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