Desflurane Anesthesia After Sevoflurane Inhaled Induction Reduces Severity of Emergence Agitation in Children Undergoing Minor Ear-Nose-Throat Surgery Compared with Sevoflurane Induction and Maintenance: Retracted

Abstract

Emergence agitation may occur after general anesthesia with volatile anesthetics in children. We designed this study to examine the emergence behavior of children undergoing ear-nose-throat surgery after sevoflurane induction and desflurane maintenance versus both sevoflurane induction and maintenance using a recently published Pediatric Anesthesia Emergence Delirium (PAED) scale. In 38 premedicated children aged 12 mo to 7 yr mask induction with sevoflurane was performed and they were randomly assigned to receive either sevoflurane (n = 19) or desflurane (n = 19) for maintenance of general anesthesia. Time to tracheal extubation, modified Aldrete score, emergence behavior, recovery complications, and pain scores were assessed. The PAED scale showed a significant advantage for desflurane (6 [0-15] versus 12 [2-20], maximum total score of 20 for severe agitation). Time to extubation was significantly shorter with desflurane than with sevoflurane (5.4 +/- 1.4 versus 13.4 +/- 1.8 min). The modified Aldrete score on arrival in the postanesthesia care unit (PACU) was significantly lower in children receiving sevoflurane for maintenance. Time to discharge from PACU to normal ward and the incidence of adverse effects were not significantly different between the groups. In conclusion, the use of desflurane for maintenance of anesthesia after sevoflurane induction in children is associated with less severe emergence agitation and faster emergence times.

Fascia iliaca compartment block reduces emergence agitation by providing effective analgesic properties in children

“…The reliability and validity of the PAED scale have been confirmed by several studies, and the average PAED score when sevoflurane is used is 7.2 ± 4.5 [11] or 12 (range, 2-20) [22]. In this study, the PAED score on arrival at the PACU was 7.3 for the FICB group and 10.4 for the control group.…”

Comparative Study of Recovery after Sevoflurane versus Halothane Anaesthesia in Adult Patients

“…Sale et al [10], concluded that infants woke up faster from general anaesthesia when maintained with desflurane as compared to sevoflurane, but there was no difference in postoperative respiratory events between the groups. Mayer et al [11], concluded that the use of desflurane for maintenance of anesthesia after sevoflurane induction in children is associated with less severe emergence agitation and faster emergence. Macario et al [12], concluded that patients receiving desflurane recovered one to two minutes earlier in the operating room than patients receiving sevoflurane.…”

The Effect of Gabapentin Premedication on the Emergence Delirium in Pediatric Patients Undergoing Circumcision Under Sevoflurane Anesthesia

“…(17,18) Mayer ve ark. 'nın (19) sevofluran indüksiyonu sonrasında anestezi idamesinde desfluran ve sevofluranı karşılaştırdığı bir çalışmada da, desfluran alan grupta derlenmenin daha hızlı olduğu, postoperatif ajitasyonunun ise sevofluran grubunda anlamlı olarak yüksek olduğu gösterilmiştir.…”