Desiging a high speed electrostatic micro-actuator with an electrical stopper useable for biological microinjection

Gilani, A. Ghanadzadeh; Moghadam, Reza Askari; Koohsorkhi, Javad; Fard, Hassan Ghafoori

doi:10.1109/icrom.2015.7367824

Cited by 2 publications

(2 citation statements)

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“…The conventional borosilicate glass capillaries, produced through pipette pulling, micro-forging and grinding, has been very popular in IVF Laboratory for a long time [63] because of the ability to sanitize and sterilize on-site by the physician himself made them extremely cost-effective. However, due to the requirement of an experienced operator, the glass pipette is most probably will be overthrown by the innovative MEMS-based injectors [61,64]. In recent times, MEMS-based injection is much popular in drug injection and cancer cell treatments.…”

Section: Mems-based Sperm Injectionmentioning

confidence: 99%

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The Role of MEMS in In-Vitro-Fertilization

Wijegunawardana

Amarasinghe

2021

Adv. Technol.

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The assisted reproduction has been considered a viable solution for the infertility of humankind for more than four decades. In-Vitro-Fertilization (IVF) is one of the most successful assisted reproduction techniques, where the reproductive cell of the female partner is fertilized outside of her body. Initially, the IVF process has been conducted manually by an experienced embryologist. However, even with a highly experienced individual, the operation had extremely lower success rates due to the limited control in environmental conditions and the requirement of precise movements. Therefore, to address this technological deficit, the feasibility of the mechatronics devices for IVF procedures has been investigated. Among the different mechatronics concepts, micro-electromechanical system (MEMS) technologies have been gradually attracted to the IVF process and improved its capabilities. The purpose of this paper is to present a brief overview of the role of MEMS technologies in IVF. The article classifies the MEMS technologies in IVF based on their application in order to emphasize its contribution. In addition, the article extensively discusses the state-of-the-art mechatronic techniques utilized in Intracytoplasmic Sperm Injection (ICSI), one of the most popular techniques used in IVF. This review article expects to become extremely beneficial for the engineering researchers new to this field who seek critical information on IVF in simple terms with highlights on the possible advancements and challenges that may emerge in the future.

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Section: Mems-based Sperm Injectionmentioning

confidence: 99%

“…Its invasion of the ICSI is yet to be initiated. For instance, in [64] a novel microinjector has been extensively analysed for oocyte penetration and shown promising results in terms of oocyte damage.…”

Section: Mems-based Sperm Injectionmentioning

confidence: 99%