Liquid CO2 can absorb heat via phase change and generates cryogenic CO2 which can effectively solve the problem of thermal damage in the deep coal mining process. The CO2 cycle refrigeration device system is designed to effectively cool down the working surface of the mine in which CO2 is cyclically utilized. COMSOL Multiphysics simulation software is used to characterize the CO2 cycle refrigeration system in mine of the heat transfers process between CO2 and the air flow in tunnel. The results show that the reduction of steady air flow temperature reach at 8 °C in the tunnel by CO2 cycle refrigeration system before the air flow into work face. we analyzed the influence of main parameters on refrigeration system and gets the results:1) The refrigeration system get higher cooling efficiency of cryogenic CO2 when the ventilation velocity of local fan is increased, and the temperature of outlet CO2 and steady air flow in tunnel has increased; 2) Increasing the CO2 flow, the refrigeration effect of the system is enhanced obviously, but CO2 refrigeration capacity utilization ratio is reduced; 3) Increasing the length of helical tube would led to use CO2 refrigerating capacity more efficiently; 4) The cooling effect of the cooling system can be improved obviously by lowering the the CO2 cooling temperature.