Design and application of novel functional dyes containing polymers for biosensors and organic syntheses

Abstract

Abstract

A Self‐Powered Ethanol Biosensor

“…The biocatalyst was entrapped in a phenothiazine modified polymer which catalyzes the regeneration of the cofactor NAD + . [37][38][39][40][41][42] The rather low redox potential of the polymer-bound phenothiazine moieties ensures a high OCV of the corresponding biofuel cell. However, at these negative potentials undesired O 2 reduction at the anode side might become an issue.…”

“…[35,36] The combination of such a biocathode with an NAD + -dependent ADH-based bioanode should provide a high OCV if a low potential redox mediator (e. g. redox dyes or quniones) is used for the oxidation of NADH at the anode. Polymer-bound phenothiazine dyes which are reduced at rather negative potentials in a 2e À /nH + step to their corresponding leuco forms (where n is the number of transferred protons and depends on the pH value) are well known redox mediators for the regeneration of NAD + [37][38][39][40][41][42][43] and were used earlier for the fabrication of polymer-based low potential bioanodes. [43][44][45][46] Thus, we considered such bioanodes as promising candidates for the design of enzyme electrodes comprising NAD + -dependent ADH as biological selectivity element.…”

Preparation and electrocatalytic properties of the TBO/nafion chemically-modified electrodes

“…The film exhibited an enhanced stability and as a good barrier to [Fe(CN) 6 ] 3À ions [9]. Recently, the carbon paste electrode with toluidine blue O covalently immobilized on the silica gel electrode was developed and used in determination of NADH [10,11]. Several polymers containing covalently or electrostatically attached TBO molecules modified electrodes were developed and tested as electron mediators or relay systems to GDH and NAD catalyzed glucose oxidation [12,13].…”

A Facile Synthesis of Poly(acrylanilide-co-acrylic Acid)

“…In recent years, the aromatic amide derivatives of poly(acrylic acid) (PAAc) and poly(methacrylic acid) (PMAc) have been paid much attention because of their ease of functionalization and processing, good performance, excellent physical and chemical stability 1 . They show potential applications in biosensors and biomedical fields [2][3][4][5][6][7] , drug delivery systems 8,9 , detection and analytical chemistry fields [10][11][12][13] and optical materials [14][15][16] . These poly(methacrylamides) and poly(acrylamides) with various functional groups could be prepared by polymerization of monomers.…”