This paper presents implementation of a serial bootloader for a MSP430G2553 microcontroller. It is implemented in assembly language and it is written in the information area of the microcontroller memory by using any usual tool for flashing. Then, the source of the application can be developed. The application code that is obtained by using the compiler and linker must be sent to the microcontroller. For this purpose, a serial communication between PC and the UART port of the microcontroller via an USB to serial converter is implemented. In this case a MATLAB application is run on the PC while the bootloader is run on the microcontroller. Finally, the bootloader receives and writes the application code in the main area of the Flash memory. Thus, an efficient method to update the application code, having advantages in comparison with those in literature is proposed.