2009
DOI: 10.1364/oe.17.023511
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Design and optimization of a novel surface plasmon resonance biosensor based on Otto configuration

Abstract: Abstract:A theoretical study on a novel planar waveguide surface Plasmon Biosensor is presented in this paper. The proposed biosensor has a configuration similar to the Otto excitation mechanism for surface Plasmon polaritons. The performance of the device with respect to key system parameters such as gap -width and device length is investigated using an eigenmode solver with perfectly matched layers (PML). Device resolution of 2.3×10-6 RIU has been demonstrated for an aqueous analyte.

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Cited by 64 publications
(39 citation statements)
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“…The sensitivity is defined as the wavelength shift corresponding to a unit variation of the refractive index; analytically is defined as [2]:…”
Section: Sensitivity Propertiesmentioning
confidence: 99%
“…The sensitivity is defined as the wavelength shift corresponding to a unit variation of the refractive index; analytically is defined as [2]:…”
Section: Sensitivity Propertiesmentioning
confidence: 99%
“…[1][2][3][4][5]. Amongst these, optical waveguide based SPR sensors have extra advantage of their possible integration with other optical components on a single chip [6,7].…”
Section: Introductionmentioning
confidence: 99%
“…In such sensors, mainly the LRSP mode contributes to the output power and a dip in the transmission spectrum is observed at a wavelength for which the real part of effective indices of the wave-guide mode and LRSP mode are closest. The position of the wavelength dip in such sensors is not affected by the length of the metal layer [4,9]. To maximize the sensitivity of such sensors, research studies have been mainly focused on the choice of metal, optimization of metal thickness and introduction of a high refractive index intermediate layer etc.…”
Section: Introductionmentioning
confidence: 99%
“…Presently, SPR based sensing technique is by far the most advanced form of real time label free sensing. It has been used extensively in the study of biomolecular interactions (BIA) and in the recognition of target analytes, both chemical and biological [1]- [3]. It is has therefore found several applications in the areas of food safety, biochemical technology, medicine, and other daily-life applications [4].…”
Section: Introductionmentioning
confidence: 99%
“…The largesize and the existence of several optical and mechanical components make optimization and commercial production of prism based sensors on a large scale difficult [5]. In addition, they cannot easily be miniaturized or incorporated into other systems [6], [7], resulting in the need to develop compact, robust and highly sensitive SPR biosensors that can be used for measurements outside a laboratory [2], [3], [7]- [10].…”
Section: Introductionmentioning
confidence: 99%