Design and Performance Assessment of Dielectrically Modulated Nanotube TFET Biosensor

Gedam, Anju; Acharya, Bibhudendra; Mishra, Guru Prasad

doi:10.1109/jsen.2021.3080922

Cited by 46 publications

(13 citation statements)

References 37 publications

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“…When modeling the impact of a biomolecule on performance parameters, just the dielectric constant is needed for a neutral molecule, while the dielectric constant and charge density are needed for a charged molecule. This proposed sensor is capable of detecting neutral biomolecules with various dielectric constants, including streptavidin, which has K = 2.1 (used for nucleic acid and lipid detection), protein, which has K = 8 (required for tissue repair), and biotin, which has K = 2.63 (which controls blood sugar) [11]. This biosensor can also be used to detect charged biomolecules like DNA, which have a range of dielectric constants of K = 1 to 64 [10].…”

Section: Resultsmentioning

confidence: 99%

“…This biosensor can also be used to detect charged biomolecules like DNA, which have a range of dielectric constants of K = 1 to 64 [10]. However, K = 6 is a typical value for the dielectric constant of DNA [11]. The literature revealed that the charge density (Q f ) of charged biomolecules like DNA ranges from −1 × 10 11 cm −2 to +1 × 10 12 cm −2 [12], [14].…”

Section: Resultsmentioning

confidence: 99%

“…This is possible because the immobilization of biomolecules in the cavity causes a change in the effective gate capacitance of the proposed device. Various research groups [11]- [16] have discussed the utility of FET-based dielectrically modulated biosensors. The literature contains several types of dielectric modulated biosensors, including nanosheet gate all around FETs [17], organic FETs [18], carbon nanotube FETs [3], tunnel FETs [19], and impact ionization FETs [20].…”

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confidence: 99%

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Dielectric Modulated Bilayer Electrode Top Contact OTFT for Label Free Biosensing

2023

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In this paper, dielectric modulated bilayer electrodes top contact organic field effect transistor (DMBETC-OTFT) is investigated as a biosensing device for label-free detection of biomolecules. The nanocavity used for biomolecule detection is created by etching the oxide in a conventional OTFT device. Neutral and charged biomolecules can be detected by the proposed device using their respective dielectric constants and charge densities. Subthreshold swing (SS), on-current (I ON ), and on-off current ratio (I ON /I OF F ) are the main biosensing performance characteristics computed and compared for different gate work function (φ m ) and cavity thickness (T gap ) for the proposed biosensor device. The change in drain current (I D ), as well as the I ON /I OF F ratio, have both been calculated to investigate the sensitivity of the proposed biosensor. The influence of the gate work function is also investigated to improve the sensitivity of the proposed device. According to the finding of this study, using a gate work function with a lower value results in a significant increase in sensitivity. For charged biomolecules (Q f = +1 × 10 12 cm −2 ) with dielectric constant of biomoecules (K = 12), the highest drain current sensitivity is 4.5 × 10 3 . The drain current sensitivity achieved is four times greater, when comparing the proposed device to the latest published work of metal controlled dielectric modulated OTFT-based sensor. The proposed device also has a high I ON /I OF F sensitivity of 4.60 × 10 2 when V GS = -3.0 V and V DS = -1.5 V. In light of its high sensitivity, low cost, and bio-compatibility, the DMBETC-OTFT biosensor holds great promise for the advancement of new demanding flexible biosensing applications.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Dielectric Modulated Bilayer Electrode Top Contact OTFT for Label Free Biosensing

2023

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“…28,29 The fabrication process of nanotube (core-shell) TFET is reported in various works of literature. 25,[30][31][32][33][34][35] In the proposed junctionless double cavity nanotube TFET biosensor structure, the fabrication process steps incorporate both charge-plasma technique and nanotube (core-shell) TFET device designing. The detailed expected fabrication process flow of the biosensor device is shown in Fig.…”

Section: Fabrication Processmentioning

confidence: 99%

“…The deposition of SiO 2 (step 28 ) as a spacer, and again deposition of a thin layer of spacer (step 29 ) in core (inner) section side walls to avoid direct contact between intrinsic silicon and core gate metal (Mo). The deposition of inner gate metal (Mo) and inner gate contact can be done in (step 30 -step 32 ). For the sensing of biomolecules, outer and inner nanogap cavities must be created.…”

Section: Fabrication Processmentioning

confidence: 99%

Design of a Double Cavity Nanotube Tunnel Field-Effect Transistor-based Biosenser

Gedam

Acharya

Mishra

2022

ECS J. Solid State Sci. Technol.

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We focus on the concept of a junction-less tunnel transistor to suggest and simulate a dielectric modulated double cavity nanotube TTunnel Field-Effect Transistor as a biosensor. The proposed biosensor works as a label-free detector about dielectric constant (K) and charge density (ρ). In this, for neutral biomolecules (streptavidin and 3-aminopropyl-triethoxysilane) and charged biomolecule (deoxyribonucleic acid) are used for detection by the proposed sensor.The inner and outer cavities of the nanotube biosensor provide a large area for the stabilization of biomolecules and take advantage of the benefits of material solubility. The sensing capability of the proposed device investigates various DC performance parameters for the different dielectric biomolecules and charge densities. Further, the effect of substitution of SiO2 gate insulating layer by HfO2 also studies the sensing capability of the proposed biosensor. Moreover, a relative study of the biosensor for the presence and absence of inner and outer nanogap cavities performs in terms of different DC components to analyze the sensitivity variation.

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TunnelFET: Principles and Operations

Ahangari

2024

Advanced Nanoscale MOSFET Architectures

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Design and Performance Assessment of Dielectrically Modulated Nanotube TFET Biosensor

Cited by 46 publications

References 37 publications

Dielectric Modulated Bilayer Electrode Top Contact OTFT for Label Free Biosensing

Dielectric Modulated Bilayer Electrode Top Contact OTFT for Label Free Biosensing

Design of a Double Cavity Nanotube Tunnel Field-Effect Transistor-based Biosenser

TunnelFET: Principles and Operations

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