Design and preparation of a biomedical titanium alloy with low elastic modulus and high antibacterial property based on Ti-Mo-Ag system

Cui, Shenshen; Liu, Shuo; Nie, Jing‐Jun; Chen, Dafu; Wu, Xinbao; Qin, Gaowu; Zhang, Erlin

doi:10.1016/j.jallcom.2022.164639

Cited by 26 publications

(7 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Good corrosion resistance is a basic requirement of titanium alloy as a biomedical titanium alloy. Figure 15a summaries the reported self-corrosion current density of several titanium alloys in simulated body fluid against the elastic modulus [10,11,[26][27][28]. It can be concluded that TNZ-3Cu(T6) exhibited the lowest corrosion density and a low modulus among all these reported titanium alloys.…”

Section: Mechanical and Corrosion Propertiesmentioning

confidence: 95%

“…Figure 15b shows the elastic modulus of titanium alloys and the antibacterial rate of the alloy against S. aureus. Ti-13Nb-13Zr-10Cu [27], TNZ-3Cu, TNZ-5Cu [10], TNZ-7Cu, Ti-15Mo-10Ag [28] and Ti-13Nb-13Zr-13Ag [11] alloys all have low elastic modulus and good antibacterial effect. However, with the consideration of corrosion resistance in Figure 15b, TNZ-3Cu exhibited good comprehensive properties: low elastic modulus, very good corrosion resistance, and acceptable antibacterial property.…”

Section: Antibacterial Propertiesmentioning

confidence: 99%

See 1 more Smart Citation

The Influence of Copper Content on the Elastic Modulus and Antibacterial Properties of Ti-13Nb-13Zr-xCu Alloy

Mao

Shi

Wang

et al. 2022

Metals

Self Cite

View full text Add to dashboard Cite

Device-related infection or inflammatory and stress shield are still the main problems faced by titanium alloy implants for long-term implantation application; therefore, it is of great significance to design an alloy with low elastic modulus and good antibacterial properties as well as good biocompatibility. In this paper, Ti-13Nb-13Zr-xCu(x = 3, 7 wt.%) alloys were designed and prepared to reveal the influence of Cu content on the elastic modulus and antibacterial property. X-ray diffractometer, metallographic microscope, scanning electron microscope, and transmission electron microscope were used to study the phase transformation, microstructure, mechanical properties, antibacterial properties, and cytotoxicity of the alloys. The experimental results have demonstrated that the antibacterial performance and the elastic modulus were significantly improved but the corrosion resistance deteriorated with the increase of the copper content. Ti-13Nb-13Zr-3Cu with a low modulus of 73 GPa and an antibacterial rate of over 90% against Staphylococcus aureus (S. aureus) exhibited great potential as a candidate for implant titanium in the future.

show abstract

Section: Mechanical and Corrosion Propertiesmentioning

confidence: 95%

Section: Antibacterial Propertiesmentioning

confidence: 99%

The Influence of Copper Content on the Elastic Modulus and Antibacterial Properties of Ti-13Nb-13Zr-xCu Alloy

Mao

Shi

Wang

et al. 2022

Metals

Self Cite

View full text Add to dashboard Cite

show abstract

“…It can also target the mitochondria in the cytoplasm to produce ROS [63] until some serious DNA damage is induced [64], which then leads to mutations and genotoxic effects, thereby killing bacteria. At the same time, the precipitation of the Ti 2 Ag phase and Ag-rich phase in Ti-Ag can also lead to the rupture of bacterial cell membranes and the death of bacteria [36,65]. The anodic oxidation coating on the Ti-Ag sample isolated the direct contact between the Ti 2 Ag phase and the bacteria, thereby reducing the antibacterial ability.…”

Section: Antibacterial Propertymentioning

confidence: 99%

Effect of Anodic Oxidation Pulse Voltage on Antibacterial Properties and Biocompatibility of Ti-Ag Alloy

Ma,

Yan,

Shi

et al. 2024

Coatings

Self Cite

View full text Add to dashboard Cite

For the application of titanium and titanium alloys in orthopedic implant materials, the antibacterial properties and cell biocompatibility determine whether the implant surgery is successful. In this study, a functional anodic oxidation (AO) coating was successfully prepared to modify the surface of Ti-Ag alloy. The surface characteristics of the anodized Ti-Ag alloy were analyzed using techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and contact angle measurements. The corrosion characteristics of Ti-Ag samples were tested by an electrochemical workstation. In addition, the antibacterial properties and cell activity were studied by the plate count method and MC3T3-E1 cell staining. The results indicate that the AO process can generate a multi-functional TiO2/Ag2O coating with a large number of block and flower-like structures on the surface of a Ti-Ag alloy. When the AO voltage of the sample is 120 V, the maximum roughness is 0.73 μm and the minimum wetting degree is 23°, which improves the biocompatibility. The corrosion test results show that AO treatment can improve the corrosion resistance of a Ti-Ag alloy. The oxidation voltage is 20 V and the coating has the best corrosion resistance. The corrosion open circuit potential (Eocp) is 107.621 mV and the corrosion current density (icorr) is 2.241 × 10−8 A·cm−2. This coating can promote ion release and show more than 99% of a strong antibacterial ability against S. aureus. The results of the compatibility evaluation by cultured cells showed that the multifunctional coating formed by the anodic oxidation process did not cause cytotoxicity and promoted the adhesion of MC3T3-E1 cells.

show abstract

“…Titanium and its alloys are used as dental implants to solve the severe oral problems that result from diseases, accidents, or even caries due to their fascinating properties like excellent biocompatibility, high corrosion resistance, acceptable strength-to-weight ratio, low elastic modulus, and low density [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Synergetic Effect of Essential oils and Calcium Phosphate Nanoparticles for Enhancement the Corrosion Resistance of Titanium Dental Implant

Zaher,

Hefnawy,

Medany

et al. 2023

Preprint

View full text Add to dashboard Cite

Calcium phosphate (CaPO4) coating is one of various methods that is used to modify the topography and the chemistry of Ti dental implant surface to solve sever oral problems that result from diseases, accidents, or even caries due to its biocompatibility and ability to remineralization. In this work, anodized (Ti-bare) was coated by CaPO4 prepared from amorphous calcium phosphate nanoparticles (ACP-NPs) and confirmed the structure by X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FT-IR) techniques. Ti-bare was coated by prepared CaPO4 through the casting process, and the morphology of Ti/CaPO4 was characterized by scanning electron microscope (SEM) where the nano-flakes shape of CaPO4 and measured to be 60 ~ 80 nm was confirmed. The stability of Ti-bare and coated Ti/CaPO4 was studied in a simulated saliva solution using electrochemical impedance spectroscopy (EIS) and linear polarization techniques to deduce their corrosion resistance. Furthermore, three essential oils (EO), Cumin, Thyme, and Coriander, were used to stimulate their synergistic effect with the CaPO4 coat to enhance the corrosion resistance of Ti implant in an oral environment. The fitting EIS parameters based on Rs[RctC]W circuit proved that the charge transfer resistance (Rct) of Ti/CaPO4 increased by 264.4, 88.2, and 437.5% for Cumin, Thyme, and Coriander, respectively, at 2% concentration. Our new results confirmed that it is necessary to maintain the positive effect of the components of the oral environment and their ability to synergize with the material of the modified Ti surface to ensure the success of Ti implantation. Thus, the use of EO with coat Ti/CaPO4 proved great corrosion resistance value, which will enhance the remineralization process of the teeth.

show abstract

Design and preparation of a biomedical titanium alloy with low elastic modulus and high antibacterial property based on Ti-Mo-Ag system

Cited by 26 publications

References 54 publications

The Influence of Copper Content on the Elastic Modulus and Antibacterial Properties of Ti-13Nb-13Zr-xCu Alloy

The Influence of Copper Content on the Elastic Modulus and Antibacterial Properties of Ti-13Nb-13Zr-xCu Alloy

Effect of Anodic Oxidation Pulse Voltage on Antibacterial Properties and Biocompatibility of Ti-Ag Alloy

Synergetic Effect of Essential oils and Calcium Phosphate Nanoparticles for Enhancement the Corrosion Resistance of Titanium Dental Implant

Contact Info

Product

Resources

About