Thermal management in automobiles is necessary to minimize energy usage while achieving a high level of occupant thermal perception. As the freedom of in-vehicle activity increases with autonomous driving, considering convenience becomes even more important, and, at the same time, the need for thermal management in electric vehicles is expected to increase. While it is necessary to consider the characteristics of the future mobility environment, there is still a lack of research that takes into account these changes in thermal management and proposes future research directions. Therefore, the purpose of this study is to explore basic research directions based on national R&D project cases and to provide a comprehensive overview. The environmental changes that need to be considered in thermal management research include the diversification of future transportation types and usage purpose diversification, the characteristics of electric vehicles, changes in the interior and exterior design of autonomous vehicles, personalized air conditioning environments, and dynamic thermal management according to occupant in-vehicle activity. This study provides an understanding of the overall field, and can help identify challenges, solutions, and ideas. Although this study provides conceptual considerations for research directions, future research is needed to identify detailed factors related to technology, environment, and human factors.