Design and validation of an indicator gas injector for multiple gas washout tests in mechanically ventilated patients

Huygen, P. E. M.; Feenstra, B. W. A.; Holland, Wim; İnce, Can; Stam, Henk J.; Bruining, H. A.

doi:10.1097/00003246-199007000-00015

Cited by 13 publications

(12 citation statements)

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“…A limitation common to both our injector method and that of Jonmarker [11] is that these techniques can only be applied during IPPV and PEEP ventilation, as the inspiratory gas flow has to be constant. If necessary, the previously described premix method [1] can be used to perform wash-out tests in the IMV mode [14]. In other ventilatory settings or spontaneous ventilation where the inspiratory flow is not constant, the method of East [7] or Larsson [9] can be applied.…”

Section: Discussionmentioning

confidence: 99%

“…The respiratory flow is measured with a pneumotachograph (Fleisch-2, Gould-Godard, The Netherlands), connected to a differential pressure transducer (Validyne MP 45-14-871, 0-2mBar, Northridge, CA, USA), placed near the mouth. All the data are sampled by a computer (PDP-11, DEC, Maynard, MA) at 100 Hz and the EEV is calculated using the algorithm of Zwart [12] and Huygen [1,13], based on the relation between the dilution of the indicator gas in the lung and the net amount of indicator gas washed out.…”

Section: Measurement Set-upmentioning

confidence: 99%

“…This test can be used to identify both restrictive and obstructive lung diseases [1,2]. There are already several methods described to perform wash-out tests.…”

mentioning

confidence: 99%

“…We previously described a device for injecting indicator gases for wash-out tests in mechanically ventilated patients [1] where the indicator gas is mixed with the ventilatory gases prior to entering the ventilator (pre-mix). This method can only be used with a low pressure gas inlet ventilator and cannot achieve a perfect step-wise change in the indicator gas fraction during the initial breaths of a wash-out at the mouth of the patient.…”

mentioning

confidence: 99%

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A simple device to inject indicator gas for wash-out tests during mechanical ventilation

et al. 1992

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Abstract.Objective: To evaluate a simple device which injects a constant fraction of indicator gas to the inspiratory mixture for performing multi-breath wash-out tests during controlled ventilation. Design: the technique in which the indicator gas is injected at the mouth of the patient (post-mix) is compared with the technique where the indicator gas is administered in the bellows of the ventilator (pre-mix). Setting." Surgical Intensive Care Unit of a University Hospital. Patients." 10 post-operative mechanically ventilated patients. Interventions: None. Measurements and results: 3 wash-out tests with the post-mix and 3 wash-out tests with the pre-mix method were performed within an hour on every patient. The calculated mean end expiratory lung volume (EEV) was 1.91 _+0.871 with the post-mix technique and 1.89_+0.881 with the premix technique. There was a good agreement with a mean difference of -1.9_+6.5% in the calculated EEV values by the two different techniques. Conclusion: The described injector is an affordable device, is easy to assemble and can be incorporated in most electronically regulated ventilators to perform multi-breath indicator gas wash-out tests for pulmonary monitoring at the bed side of ICU patients.

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Section: Discussionmentioning

confidence: 99%

Section: Measurement Set-upmentioning

confidence: 99%

“…This test can be used to identify both restrictive and obstructive lung diseases [1,2]. There are already several methods described to perform wash-out tests.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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A simple device to inject indicator gas for wash-out tests during mechanical ventilation

et al. 1992

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“…This results in an optimal use of measurement time which can be advantageous in the rapidly changing condition of the critically ill patient. The obtained data, besides providing patient lungfunction tests [12,23,24], can be used for basic lung-physiological research. With the described system measurements have been performed on 60 spontaneously breathing patients.…”

Section: Discussionmentioning

confidence: 99%

PDPS: A pulmonary data processing system for assessment of gas exchange properties by multiple gas wash-out

Huygen

Feenstra

Hoorn

et al. 1991

Computer Methods and Programs in Biomedicine

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A data acquisition and processing system for the analysis of inert gas wash-out tests is described. The described system is in clinical use on spontaneously breathing patients as well as on mechanically ventilated Intensive Care patients. It combines several analysis techniques with an aim to provide a deeper insight into the nature of existing ventilation inhomogeneity than the individual techniques alone can provide. The signals measured are the respiratory flow, the fractions of one or two indicator gases washing out and the fractions of the metabolic gases oxygen and carbon dioxide. Analysis of these signals provides information concerning the end-expiratory lung-volume, distribution of ventilation and perfusion in the lung, the role of diffusion in the ventilation process and the metabolic oxygen uptake and CO2 release. This article describes the algorithms used and the results that are presented.

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Determination of Lung Volume in the ICU

Burchardi¹,

Wrigge²,

Sydow³

1998

Yearbook of Intensive Care and Emergency Medicine

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Design and validation of an indicator gas injector for multiple gas washout tests in mechanically ventilated patients

Cited by 13 publications

References 0 publications

A simple device to inject indicator gas for wash-out tests during mechanical ventilation

A simple device to inject indicator gas for wash-out tests during mechanical ventilation

PDPS: A pulmonary data processing system for assessment of gas exchange properties by multiple gas wash-out

Determination of Lung Volume in the ICU

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