To improve the wear resistance and mineral crushing performance of grinding rollers in cement, mining, and other engineering fields, a striped groove morphology was designed on the normal grinding roller surface in this study. The wear resistance of grinding rollers with different striped groove parameters and the crushing performance of quartz sand were tested with a purposely designed device. The depth and number of striped grooves were used as the structural parameters of the striped grooves, and the test protocol was designed with the experimental design method. The results showed that the wear resistance and crushing performance of the grinding roller with striped grooves were better than those of the smooth grinding roller for quartz sand. For example, the wear of the 3# bionic grinding roller was reduced by 53.58% compared with the average wear amount of a normal grinding roller, and the crushing effect of the quartz sand was also improved. The regression equation between the stripe depth, number of stripes, and wear amount of the grinding roller was constructed on the basis of the multiple orthogonal regression method. It was found that the influence of the striped groove depth on the wear amount of the grinding roller was greater than that of the distribution number of the striped grooves. According to the results and the analysis the striped grooves distributed on the grinding roller’s surface caused the friction state between the quartz sand and the grinding roller to be in a state of sliding friction, and the wear amount was reduced. Striped grooves on the grinding roller surface might also change the stress state of the quartz sand in the crushing process. Additionally, the performance of the bionic grinding roller in crushing quartz sand was improved, and the wear amount of the bionic grinding roller was also reduced compared with that of the normal grinding roller.