Design of 3‐aminophenol‐grafted polymer‐modified zinc sulphide nanoparticles as drug delivery system

Abstract

Zinc sulphide (ZnS) nanoparticles were synthesized by the coprecipitation method. The ZnS nanoparticle surface was polymerized with allyl glycidyl ether (AGE), and 3aminophenol was then deposited as a ligand on nanosorbent. The modified nanosorbent was investigated with Fourier transform infrared spectroscopy and thermogravimetric analysis. The particle size of the modified nanosorbent was studied with scanning electron microscopy. Some characteristic factors of the adsorption process such as pH and time were investigated for famotidine using the modified nanosorbent. The equilibrium adsorption study of famotidine by 3-aminophenol-grafted AGE/ZnS was analysed by adsorption isotherms of the Langmuir, Freundlich, and Temkin models. The famotidine-releasing process was investigated in simulated biological fluids (intestinal fluid at pH of 7.4 and gastric fluid at pH of 1.2) and demonstrated 65% and 73% famotidine release during periods of 30 h (pH = 7.4) and 60 min (pH = 1.2), respectively. These results reveal the optimal performance of 3-aminophenol-grafted AGE/ZnS for sustained drug delivery.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

An alternative method of dispersive solid‐phase extracting Hg (II) from environmental aqueous solutions using carboxylic functionalized carbon nanotubes

“…Dubinin–Radushkevich model was applied to understand the Hg 2+ sorption type. This type is a form of empirical isotherm and it is expressed the Gaussian energy distribution by adsorbate sorption mechanism on a heterogeneous surface and a linear model is given as [40, 41]: $$$$\begin{equation}In\,{q_e} = In\,{q_D} - {B_D}{(In\,RT(1 + 1/{C_e}))^2}\end{equation}$$$$…”

“…Dubinin-Radushkevich model was applied to understand the Hg 2+ sorption type. This type is a form of empirical isotherm and it is expressed the Gaussian energy distribution by adsorbate sorption mechanism on a heterogeneous surface and a linear model is given as [40,41]:…”

Synthesis of chitosan functionalized magnetic carbon nanotubes for dispersive solid‐phase extraction of bromocresol green

“…Such observations demonstrated that accessibility of empty Fe 3 O 4 @MWCNT-CN binding sites at initial stages of dye adsorption and after that equilibrium is reached, occupying other empty sites would be difficult. This is reasoned by the repellent forces between the bromocresol green molecules and Fe 3 O 4 @MWCNT-CN [31,32].…”

Fabrication of superparamagnetic adsorbent based on layered double hydroxide as effective nanoadsorbent for removal of Sb (III) from water samples

“…At this stage, the experimental data on adsorption equilibrium with Freundlich, Langmuir, and Temkin isotherms were examined. The equations for isotherm models of Langmuir, Temkin, and Freundlich are as follows, respectively [47, 48]. where Q 0 is the highest antimony ions sorption capacity at Fe@Mg‐Al LDH (mg/g) and b is the constant of the Langmuir Equation (L/mg), k T (L/g) and B (J/mol) are the constants of the Temkin Equation, K f ((mg/g)·(L/mg) 1/ n ) and n are the constants of the Freundlich Equation, C e (mg/L) is the concentration of the adsorbate in the liquid phase after reaching equilibrium, and q e (mg/L) is the amount of the adsorbate per unit mass of Fe@Mg‐Al LDH [49].…”

“…At this stage, the experimental data on adsorption equilibrium with Freundlich, Langmuir, and Temkin isotherms were examined. The equations for isotherm models of Langmuir, Temkin, and Freundlich are as follows, respectively [47,48].…”