Light-emitting diodes (LEDs) have been intensively studied for white-light lighting since their luminous efficacy exceeds 50 lm/W. Currently, the luminous efficacy of an LED light tube/bulb is almost above 100 lm/W. LED solid-state lighting (SSL) has unequivocally become the major light source in general lighting. The fact of high efficiency and other advantages of LED SSL is enough to penetrate all lighting scenarios. However, what people demand from new-generation lighting is not only in energy efficiency but also in lighting quality. Thus, how to make the lighting more user friendly is one of the important issues, and, here, optics is the key point. For making a collection with the discussions of the novel optical design in enhancing lighting efficiency in a more uniform illumination pattern, in higher sharpness for special lighting, in a higher signal-to-noise ratio for communication, in more functions for new applications, etc., this Special Issue of “Advanced LED Solid-State Lighting Optics” focuses on advanced applications in all aspects.