Design of a reduced-graphene-oxide composite electrode from an electropolymerizable graphene aqueous dispersion using a cyclodextrin-pyrrole monomer. Application to dopamine biosensing

Fritea, Luminița; Goff, Alan Le; Putaux, Jean‐Luc; Tertiş, Mihaela; Cristea, Cécilia; Săndulescu, Robert; Cosnier, Serge

doi:10.1016/j.electacta.2015.07.124

Cited by 52 publications

(19 citation statements)

References 32 publications

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“…Electrodes modified with conducting polymers received considerable interest because of their high stability, good electronic properties and catalytic ability [13,15]. Furthermore, the conductive polymers can be easily deposited on the electrode by the electrooxidation of their monomers.…”

Section: Cds Based Conducting Polymersmentioning

confidence: 99%

Recent advances for cyclodextrin-based materials in electrochemical sensing

Zhu

Chen

2016

TrAC Trends in Analytical Chemistry

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Section: Cds Based Conducting Polymersmentioning

confidence: 99%

Recent advances for cyclodextrin-based materials in electrochemical sensing

Zhu

Chen

2016

TrAC Trends in Analytical Chemistry

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“…Thus, the thickness of diffusion layer is increased as the time passes through and the concentration of ferrocyanide at the electrode surface had further diffused from the bulk solution. The faster the scan rate, the shorter the diffusion layer; hence greater the electron transfer [23]. Besides, the flux to the electrode is smaller at lower scan rate compare with the higher scan rate and the current is directly proportional to flux toward the electrode.…”

Section: (A) (B )mentioning

confidence: 77%

The Electrochemical Behavior of Zinc Oxide/Reduced Graphene Oxide Composite Electrode in Dopamine

2018

MJAS

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Zinc oxide/reduced graphene oxide (ZnO/rGO) composite was synthesized via the modified Hummers' method. The presence of ZnO composite on the rGO sheets was confirmed by Scanning Electron Microscope (SEM), X-Ray Diffractometer (XRD) and Fourier Transform Infrared (FTIR) spectrometer. FTIR result showed the formation of ZnO/rGO with the presence ZnO stretching peak and the surface of ZnO/rGO was found to have better morphology with functionalized groups attached to it. XRD analysis also confirms the formation of ZnO/rGO composite by wurtzite structured indexed peak of the diffractogram. The ZnO/rGO composite was drop on the surface of GCE by drop casting method to increase the electrocatalytic activities of bare GCE. The electrochemical behaviour of ZnO/rGO modified electrode shows the enhancement in electron transfer and the system is diffusion-controlled. The electrochemical studies also revealed that the ZnO/rGO/GCE dramatically increased the current response against the dopamine (DA), due to the synergistic effect emerged between ZnO and rGO. This attributed that ZnO/rGO/GCE could exhibit excellent electrocatalytic activity and effective electron transfer kinetics towards the oxidation of DA. Therefore, the ZnO/rGO/GCE could be used to determine the DA concentration and provide an ideal matrix for clinical applications.Keywords: zinc oxide, reduced graphene oxide, composite materials, dopamine, electrocatalysis Abstrak Komposit zink oksida/grafin oksida terturun (ZnO/rGO) telah disintesis melalui kaedah Hummer terubahsuai. Kehadiran komposit ZnO pada lapisan rGO telah diujikan oleh mikroskop imbasan elektron (SEM), Pembelauan sinar X (XRD) dan Inframerah transformasi Fourier (FTIR). Keputusan FTIR menunjukkan pembentukan ZnO/rGO dengan kehadiran puncak ZnO dan permukaan ZnO/rGO didapati mempunyai morfologi yang lebih baik dengan kumpulan berfungsi melekat padanya. Analisis XRD juga menunjukkan pembentukan komposit ZnO/rGO melalui diffraktogram indeks puncak struktrur wurtzit. Komposit ZnO/rGO telah diubahsuai dengan elektrod karbon berkaca (GCE) dengan menggunakan kaedah alas titis. Perlakuan elektrokimia ZnO/rGO/GCE menunjukkan peningkatan dalam pemindahan elektron dan sistem adalah proses serapan terkawal. Kajian elektrokimia mendedahkan bahawa respon arus ZnO/rGO/GCE meningkat terhadap DA, disebabkan kesan sinergi antara ZnO dan rGO. Ini disebabkan respon arus ZnO/rGO/GCE boleh mempamerkan aktiviti elektropemangkin yang berkesan terhadap kinetik pemindahan elektron DA. Oleh itu, ZnO/rGO/GCE boleh digunakan untuk menentukan kepekatan DA dan menjadi pemangkin sesuai untuk aplikasi klinikal.Kata kunci: zink oksida, grafin oksida terturun, bahan komposit, dopamin, elektropemangkin ISSN -2506 Farhanini et al: THE ELECTROCHEMICAL BEHAVIOR OF ZINC OXIDE/REDUCED GRAPHENE OXIDE COMPOSITE ELECTRODE IN DOPAMINE 228Introduction Dopamine (DA) is the most significant catecholamines, belongs to the excitatory neurotransmitter family which consists of an amine group linked to a catechol structure. It has great infl...

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“…Furthermore, our method utilized a simpler and easy to fabricate matrix for tyrosinase immobilization in comparison to the complex matrix such as bilayer poly‐[β‐CD‐pyrrole/reduced graphene oxide]/poly‐[NEt 4+ ‐pyrrole], as reported by Fritea et. al and it still shows one of the lowest LOD value.…”

Section: Resultsmentioning

confidence: 94%

Tyrosinase‐Conjugated Prussian Blue‐Modified Nickel Oxide Nanoparticles‐Based Interface for Selective Detection of Dopamine

et al. 2017

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In this paper, we have reported fabrication of a label free dopamine biosensor with improved sensitivity and selectivity using an interface based on Prussian blue (PB) modified nickel oxide (NiO) nanoparticles (NPs) and tyrosinase enzyme conjugates. A wet chemical sol‐gel method was used to synthesize NiO NPs followed by surface modification with PB and utilized as a matrix to immobilize tyrosinase. The structural and morphological studies of the prepared NPs were conducted using X‐ray diffraction (XRD), high resolution transmission electron microscopy (HR‐TEM), Raman and UV‐Vis spectroscopy and purity of the sample was confirmed through X‐ray photoelectron spectroscopy (XPS), energy dispersive X‐ray spectroscopy (EDX) and Fourier transform infrared spectroscopy (FTIR) studies. Subsequently, the PB modified NiO NPs were deposited onto a flexible screen printed carbon electrode (SPCE) substrate and tyrosinase enzyme molecules were immobilized onto PB‐NiO NPs functionalized SPCE by covalent immobilization for selective and sensitive detection of neurotransmitter dopamine. The enzyme immobilization was confirmed through scanning electron microscopy (SEM) and FTIR studies and the fabricated electrode was used for electrochemical detection of dopamine using cyclic voltammetry and chrono‐amperometric methods. The results of the electrochemical response studies revealed high sensitivity of 60.459 μA/nanomoles in a broad detection range (0.0075‐1.5 nanomoles) with a detection limit of 3.117 picomoles, whereas sample volume was as low as 15 μL. The proposed sensor exhibited fast response time of 24 seconds; good selectivity in presence of interferents ascorbic and uric acid; descent shelf life of 50 days with excellent reusability (>30 times with 78 % residual response). The sensor was also successfully validated with spiked real serum samples.

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Design of a reduced-graphene-oxide composite electrode from an electropolymerizable graphene aqueous dispersion using a cyclodextrin-pyrrole monomer. Application to dopamine biosensing

Cited by 52 publications

References 32 publications

Recent advances for cyclodextrin-based materials in electrochemical sensing

Recent advances for cyclodextrin-based materials in electrochemical sensing

The Electrochemical Behavior of Zinc Oxide/Reduced Graphene Oxide Composite Electrode in Dopamine

Tyrosinase‐Conjugated Prussian Blue‐Modified Nickel Oxide Nanoparticles‐Based Interface for Selective Detection of Dopamine

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