Design of the X-Ray Micro-CT Scanner TOLMI-150-10 and its Perspective Application in Non-Destructive Evaluation

Batranin, A. V.; Чахлов, С. В.; Grinev, D. V.; Капранов, Борис Иванович; Клименов, В. А.

doi:10.4028/www.scientific.net/amm.379.3

Cited by 11 publications

(7 citation statements)

References 2 publications

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“…We performed microCT scanning of two bovine IMA using TOLMI-150-10, an original microCT scanner designed in National Research Tomsk Polytechnic University [14]. For microCT, we used the following parameters: X-ray tube voltage of 100 kV, X-ray tube current of 5 mA, exposure time of 1 s per frame, angle step of 0.35°, and voxel size of 67.3 µm.…”

Section: Microct Imagingmentioning

confidence: 99%

Finite Element Analysis-Based Approach for Prediction of Aneurysm-Prone Arterial Segments

et al. 2018

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Arterial aneurysms represent a significant cause of morbidity and mortality worldwide; therefore, there is a growing need for the rapid and precise tool or method enabling to predict aneurysm emergence. The objective of this study was to develop a computer-aided method for aneurism prediction. Here we utilized a computer-based approach to establish a non-invasive, high-resolution and rapid method for the prediction of aneurysm-prone arterial segments based on combining microcomputed tomography (microCT) scanning with finite element analysis (FEA). We performed a microCT image binarization and designed a computing algorithm for FEA mesh construction, followed by application of gradient mapping and stress modeling to identify thin-walled high-stress areas responsible for the development of aneurysms. The fidelity of our computing algorithm for FEA mesh construction was similar to the commercially available software. The maximum possible error of our approach did not exceed that of either microCT or clinically available multislice computed tomography angiography scanning. Our computational approach revealed thin-walled arterial segments under a high stress, therefore potentially predicting aneurysm-prone sites. Here we demonstrate our approach for the prediction of arterial segments under a high risk of aneurysm occurrence, which should be further validated in pre-clinical models to be translated into the clinical practice.

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Section: Microct Imagingmentioning

confidence: 99%

Finite Element Analysis-Based Approach for Prediction of Aneurysm-Prone Arterial Segments

et al. 2018

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“…В современной отечественной и зарубежной научно-исследовательской и медицинской практике, метод микро-КТ с последующей постобработкой и анализом полученных томограмм, вызывает обоснованный интерес не только у клиницистов, но и у специалистов, изучающих вопросы морфологии человека и животных в норме, и при патологических состояниях. Внедрение данного метода (подхода) доказало свою состоятельность при решении задач реконструкции прецизионных биологических моделей (анатомических структур) с последующим компьютерным моделированием и исследованием имплантированных объектов в биологические ткани [18][19][20][21][22].…”

Section: âведениеunclassified

Application of Computer Microtomography in the Study of Morphostructural Peculiarities of Hard Tissues of Teeth in Early Forms of Carious Lesions

Анатольевич

Chukov

Ивановна

et al. 2018

Kuban. nauсh. med. vestnik

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Aim. The research was designed to assess the capabilities of the microcomputer tomography method with the subsequent image analysis and determination of the mineral optical density of demineralized areas to improve the early diagnosis of fissure caries of permanent molars after the eruption.Materials and methods. Using a high-resolution X-ray microtomograph “Skyscan 1176” (“Bruker”, Belgium) followed by post-processing and analysis of the obtained tomograms, 75 molars of children aged 8-11 were removed by orthodontic indications. Of the total number of teeth removed, research groups were formed – teeth without signs of demineralization and teeth with carious lesions in the stage of white, light brown, brown and black spots. In the reconstructed 2D and 3D images were identified the zones in the outer (0.05-0.5 mm), middle (0.75-1.25 mm) and inner (1.5-2.0 mm) thirds of the thickness of the enamel layer followed by the computation in the CTvox program (3.3.0-1403, Bruker-micro CT) of the averaged X-ray (mineral) density indicators. Results. According to the tomograms of the teeth of the studied groups, the average indicators of the mineral optical density of the intact teeth enamel were identified as well as the average indicators of teeth with various types of carious lesions within the enamel. The following sequence was revealed in descending order of the parameters of optical density: healthy enamel (2.47±0.12 g/cm3) – caries in the white spot stage (2.41±0.11 g/cm3) – caries in the light brown spot stage (2.32±0.07 g/cm3) – caries in the brown spot stage (2.18±0.12 g/cm3) – caries in the black spot stage (1.81±0.12 g/cm3). Identifying the correlations between the color of carious lesion and mineral density of tooth enamel broadens the understanding of the mechanisms of the development of caries pathogenesis and contributes to the improvement of therapeutic and preventive measures aimed at improving caries resistance.Conclusion. The use of microcomputer tomography in combination with other special methods characterizes fissure caries as a sequential, gradually progressing destructive process of hard tooth tissues (from focal demineralization to cavity formation), which establishes the relationship between the intensity of internal disturbances and external damage.

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“…1,в). Для максимально точного моделирования потоков и работы створчатого аппарата получали компьютерную модель биопротеза методом компьютерной микротомографии (микроКТ) [15,16] вращаться, получали серию проекций биопротеза. Разрешающая способность томографа в данной работе составила 25.4 мкм (размер вокселя), поскольку максимальное проекционное увеличение М = 5 раз было определено размером объекта.…”

Section: исследуемый протез клапана сердцаunclassified

Computer Modeling of Fluid Flow through the Heart Valve Bioprosthesis

Klyshnikov¹,

Овчаренко²,

Batranin³

et al. 2018

Math.Biol.Bioinf.

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The paper describes the features of in silico simulation of fluid flows of variable viscosity in the study of prosthetic heart valves. Computer modeling and its verification were performed on the example of the bioprosthesis "UniLine" (Russia) used in modern cardio-surgical practice. A spatial model of the object of investigation was obtained by the method of computer microtomography, followed by the reconstruction of the primitive grid in two-dimensional sections. In the numerical experiment, the immersed boundary method was used. Herein the interaction of a solid and a liquid as well as the impact of mechanics of deformation of the elements of the prosthesis, such as the winged apparatus, were taken into account. Verification of the calculation algorithm was performed in the pulsating flow setup in conditions of simulating the physiological parameters of hydrodynamics similar to those used in silico. In general, the results of the simulation are consistent with the quantitative and qualitative data of the hydrodynamic experiment. Thus, in the numerical simulation, a pressure gradient of 3.0 ± 1.1 mmHg was obtained, an effective orifice area of 2.8 cm2, a regurgitation volume of 0.1 ml/min. The experimental evaluation has shown the similar indicators: 6.5 ± 3.6 mmHg, 2.3 ± 0.6 cm2, 3.1 ± 1.7 ml/min, respectively. The described method demonstrates its promise and can be used in design and research tasks.

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Design of the X-Ray Micro-CT Scanner TOLMI-150-10 and its Perspective Application in Non-Destructive Evaluation

Cited by 11 publications

References 2 publications

Finite Element Analysis-Based Approach for Prediction of Aneurysm-Prone Arterial Segments

Finite Element Analysis-Based Approach for Prediction of Aneurysm-Prone Arterial Segments

Application of Computer Microtomography in the Study of Morphostructural Peculiarities of Hard Tissues of Teeth in Early Forms of Carious Lesions

Computer Modeling of Fluid Flow through the Heart Valve Bioprosthesis

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