Designing a novel tetradentate polyoxometalate eco-catalyst for the synthesis of β-aminocyclohexanone derivatives in water

Abstract

The synthesis of a series of known β-aminocyclohexanones has been accomplished using pentaerythrityl tetramethyl imidazolium phosphotungstate (C(MIM-PTA)4) as a new tetradentate acidic catalyst.

Immobilized Ni on TMEDA@βSiO2@αSiO2@Fe3O4: as a novel magnetic nanocatalyst for preparation of pyrido[2,3-d:6,5-d′]dipyrimidines

“…Based on the data in this table, the specic surface area of Ni-TMEDA@bSiO 2 @-aSiO 2 @Fe 3 O 4 has decreased compared to TMEDA@bSiO 2 @-aSiO 2 @Fe 3 O 4, aSiO 2 @Fe 3 O 4 and Fe 3 O 4 ; this is due to the stabilization of organic groups and nickel complexes on the mesoporous channels of magnetic silica nanoparticles. 50,51 The specic surface (S BET ) of each material can be calculated through eqn (1), where, A N 2 is atomic surface area of N 2 at 77 K (0.162 nm 2 ), N and V m are the Avogadro's number and monolayer volume, respectively (eqn (2)). 52…”

“…2,3 These materials act as an interface between homogeneous and heterogeneous catalysis for reasons such as signicant efficiency, physical and chemical stability, recyclability, large surface/volume ratio, and good biocompatibility. [1][2][3][4][5] In particular, Fe 3 O 4 nanoparticles have garnered a lot of interest in organic synthesis and other elds of science due to their unique properties. [6][7][8] Perhaps the best feature of magnetic nanoparticles, which increases the versatility of work up steps, is their simple segregation from reaction mixtures via an external magnet.…”

“…During recent decades, the design of recyclable catalysts has been greatly developed in the chemical and pharmaceutical industries. 1 Hence, anchoring catalysts to suitable solid substrates has become very important in various elds of chemical reactions. 2,3 These materials act as an interface between homogeneous and heterogeneous catalysis for reasons such as signicant efficiency, physical and chemical stability, recyclability, large surface/volume ratio, and good biocompatibility.…”

Metal‐free organic transformation: 2,6‐Pyridine dicarboxylic acid catalyzed synthesis of 5‐substituted‐1H‐tetrazoles and β‐aminoketones

“…1 H NMR spectroscopy was used to determine the stereoselectivity of β‐aminocyclohexanones, and it was discovered that the anti‐isomer was the only result of the reaction in all cases [51] …”

“…H NMR spectroscopy was used to determine the stereoselectivity of β-aminocyclohexanones, and it was discovered that the anti-isomer was the only result of the reaction in all cases. [51] Following that, the Mannich reaction's substrate scope was investigated under ideal conditions. Using the electrophile, many substituted acetophenone derivatives were studied (Table 7).…”