Designing of an Adipic acid bridged Zn(II) coordination polymer: Synthesis and biological study

Pyridyl-Isonicotinoyl Hydrazone-Bridged Zn(II) Coordination Framework with Thiophenedicarboxylato Link: Structure, Biological Activity, and Electrical Conductivity

“…The Zn−O bond (Zn1−O2, 2.051; Zn1−O3, 2.027; Zn1−O4, 2.113; and Zn1−O5, 2.415 Å) and Zn−N bond (Zn1−N1, 2.155; Zn1−N2, 2.194 Å) distances are comparable with the reported results. 36,37 The topology of the as-synthesized compound 1 (Figure 2c) belongs to the point symbol {4 ̂12.6 ̂3} for extended point symbol, [4.4.4.4.4.4.4.4.4.4.4.4.6(4).6(4).6(4)]; three digit topology is pcu, 6/4/c1; and the 6-c net for a uninodal system shows interpenetrated lattice arrangement.…”

“…34,35 This has encouraged us to explore medicinal activity of newly designed Zn-CPs/MOFs. 36,37 In this work, pyridine-4-carboxaldehyde isonicotinoyl hydrazine (pcih) and 2,5-thiophen dicarboxylic acid (H 2 tdc) are used to construct a mixed bridging 2D coordination polymer of Zn(II), {[Zn 2 (tdc) 2 (pcih) 2 ] n } (1), and the single crystal X-ray diffraction measurement has been used to determine the structure. Because of antimicrobial and antituberculotic activity of isoniazid and biological importance of Zn(II), the anticancer activity of the compound 1 is examined, which shows considerable cytotoxicity against MDA-MB 231, HCT-116, HeLa, and HepG2 cell lines (cancer cells) and has been compared with WI-38 (normal lung fibroblast cell line).…”

“…Zn-based co-ordination compounds are utilized in various biological and medicinal fields. Antimicrobacterial, anticancer, and cell imaging application are developing areas of Zn­(II)-co-ordination compounds. , This has encouraged us to explore medicinal activity of newly designed Zn-CPs/MOFs. , …”

On the Importance of H-Bonding Interactions in the Enclathration of Boric Acids in Na(I) Polymers: Experimental and Theoretical Studies

“…Saturated dicarboxylic acids also serve as suitable H-bonding acceptors [29,30], resulting in the development of bridging metal-organic compounds with various desired self-assembled architectures [31,32]. As a consequence, adipic acid has evolved as a potential bridging ligand to form interesting coordination polymers with potential applications [33][34][35]. The dicarboxylate groups of fumarate anion (an unsaturated dicarboxylate) also have the ability to coordinate with the metal centers in multidentate fashion [36].…”