Destruxin B produced by Alternaria brassicae does not induce accessibility of host plants to fungal invasion

Parada, Roxana Y.; Oka, Kazutaka; Yamagishi, Daisuke; Kodama, Motoichiro; Otani, Hiroshi

doi:10.1016/j.pmpp.2007.10.003

Cited by 23 publications

(19 citation statements)

References 9 publications

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“…In contrast, Buchwaldt and Green (1992) observed the nonhostspecific toxicity of destruxin B. Parada et al (2007) studied the host specificity of destruxin B and indicated its non-host specific nature supporting the result of Buchwaldt and Green (1992). Bains et al (1993) worked on the host specificity of homodestruxin B and observed the symptom of different severities in leaves of various non-host plants and suggested that homodestruxin B is non-host specific toxin.…”

Section: Toxins Of a Brassicae And A Brassicicolamentioning

confidence: 89%

Alternaria blight of oilseed Brassicas: A comprehensive review

Dharmendra¹,

Maurya²,

Yashwant³

et al. 2014

Afr. J. Microbiol. Res.

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Oilseed brassicas also known as rapeseed-mustard is an important group of oilseed crop in the world. These crops are susceptible to a number of diseases caused by biotic and mesobiotic pathogens. Among various diseases, Alternaria leaf blight also known as Alternaria dark spot is the most destructive disease of oilseed brassicas species in all the continents. This disease is known to be incited by Alternaria brassicae, Alternaria brassicicola and Alternaria raphani singly or by mixed infection. Alternaria leaf spot pathogens are necrotrophs and produces lesions surrounded by chlorotic areas on leaves, stems and siliquae causing reduction in the photosynthetic areas, defoliation, and early induction of senescence. Alternaria blight causes considerable reduction in quantity and quality of harvested brassica products. The Alternaria leaf blight pathogens are seedborne, soilborne and airborne. The pathogens are greatly influenced by weather with the highest disease incidence reported in wet seasons and in areas with relatively high rainfall. The concentration of conidia, age of the host plants, and wetness period on leaves also influence the severity of the disease. This paper reviews the research and development of Alternaria blight in the oilseed brassicas (rapeseed-mustard) during the past years in relation to pathogen taxonomy, biology, epidemiology, host pathogen interaction and management through chemicals, botanicals, biological, cultural, and biotechnological approaches. The paper also attempts to present future outlook and strategy for Alternaria blight of rapeseed-mustard research.

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Section: Toxins Of a Brassicae And A Brassicicolamentioning

confidence: 89%

Alternaria blight of oilseed Brassicas: A comprehensive review

Dharmendra¹,

Maurya²,

Yashwant³

et al. 2014

Afr. J. Microbiol. Res.

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“…ABR-toxin at concentrations of 0.5–1.0 μg/ml prompted water-soaked symptoms subsequently chlorosis on Brassica leaves, although non-host leaves were not affected uniform at 50 μg/ml indicating host-specific toxicity. Consequently, ABR-toxin does not only induce the preliminary colonization in host plants, but also appears to be involved in disease enlargement [123].…”

Section: Host-specific (Hsts) Toxins Of Alternaria Speciesmentioning

confidence: 99%

Alternaria host-specific (HSTs) toxins: An overview of chemical characterization, target sites, regulation and their toxic effects

2019

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“…) is a cyclodepsipeptide that was first isolated from Alternaria brassicae , the causal agent of gray leaf spot in Brassica plants . It induced clorosis and necrosis on host and nonhost plants, respectively . It was also isolated from Metarhizium anisopliae , together with its analogue destruxin A, and showed insecticidal activity .…”

Section: Fungal Metabolites and Their Synthetic Analogues Evaluated Imentioning

confidence: 99%

“…168 It induced clorosis and necrosis on host and nonhost plants, respectively. 169 It was also isolated from Metarhizium anisopliae, together with its analogue destruxin A, and showed insecticidal activity. 170 Later, destruxin B was also isolated together with additional analogues from the fungus Cordyceps indigotica.…”

Section: Destruxin Bmentioning

confidence: 99%

Toward a Cancer Drug of Fungal Origin

Kornienko

Evidente²,

Vurro

et al. 2015

Medicinal Research Reviews

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Although fungi produce highly structurally diverse metabolites, many of which have served as excellent sources of pharmaceuticals, no fungi-derived agent has been approved as a cancer drug so far. This is despite a tremendous amount of research being aimed at the identification of fungal metabolites with promising anticancer activities. This review discusses the results of clinical testing of fungal metabolites and their synthetic derivatives, with the goal to evaluate how far we are from an approved cancer drug of fungal origin. Also, because in vivo studies in animal models are predictive of the efficacy and toxicity of a given compound in a clinical situation, literature describing animal cancer testing of compounds of fungal origin is reviewed as well. Agents showing the potential to advance to clinical trials are also identified. Finally, the technological challenges involved in the exploitation of fungal biodiversity and procurement of sufficient quantities of clinical candidates are discussed and potential solutions that could be pursued by researchers are highlighted.

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Destruxin B produced by Alternaria brassicae does not induce accessibility of host plants to fungal invasion

Cited by 23 publications

References 9 publications

Alternaria blight of oilseed Brassicas: A comprehensive review

Alternaria blight of oilseed Brassicas: A comprehensive review

Alternaria host-specific (HSTs) toxins: An overview of chemical characterization, target sites, regulation and their toxic effects

Toward a Cancer Drug of Fungal Origin

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