Montmorillonite-beidellite smectites are present in amounts up to 50% in the rocks directly underlying the potential high-level radioactive waste repository horizon at Yucca Mountain, Nevada. Smectites can be significantly affected by minor changes in temperature and water vapor pressure, leading to changes in rock strength, porosity, and permeability. It is thus important to consider their behavior in a repository environment because emplacement of waste will increase temperatures and as a result change the water vapor pressures in the rocks. The thermal reactions of concern include (1) reversible collapse/expansion of the smectite layers due to loss/gain of interlayer water; (2) irreversible collapse due to loss of interlayer water and migration of interlayer cations into the 2:1 silicate layers; (3) irreversible reduction of the osmotic swelling ability through reaction in a steam atmosphere; and (4) inhomogeneous transformation of the smectite into an interstratified illite/smectite. Reversible collapse should be of minor importance because any thermally driven collapse will be reversed when water is introduced and temperatures go down. The amounts of smectite in the potential repository horizon itself are probably insufficient to give rise to rock strength problems due to reversible collapse. Reactions 2 and 4 will probably be of negligible importance due to the high temperatures and long times required for reaction. However, the irreversible reduction of osmotic swelling capacity in a steam environment may be significant in the rocks near the repository horizon. This effect on naturally occurring Na-rich smectites would probably increase permeabilities but would also provide for increased cation exchange by the smectite. Exposure of Na-smectites used for packing/backfill to a steam environment may eliminate or severely reduce the beneficial properties of the smectites in a short time, arguing against using Na-smectites for this purpose unless saturated conditions will be maintained. I.