Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial

Ikematsu, Hiroaki; Sakamoto, Taku; Togashi, Kazutomo; Yoshida, Naohisa; Hisabe, Takashi; Kiriyama, Shinsuke; Matsuda, Koji; Hayashi, Yoshikazu; Matsuda, Takahisa; Osera, Shozo; Kaneko, Kazuhiro; Utano, Kenichi; Naito, Yuji; Ishiguro, Hiroshi; Kato, Masayuki; Yoshimura, Kenichi; Ishikawa, Hideki; Yamamoto, Hironori; Saito, Yutaka

doi:10.1016/j.gie.2017.01.017

Cited by 95 publications

(85 citation statements)

References 44 publications

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“…Additionally, we clarified that BLI-bright in laser endoscopic system yielded a better polyp visibility score than WLI [9]. And a recent multicenter study showed BLI-bright improved the polyp detection rate [20]. Thus, we think the evaluation of polyp visibility scores in the video research may be useful for predicting the improvement of polyp detection about new modalities including WLI settings.…”

Section: Discussionmentioning

confidence: 79%

High Enhancement Settings for White Light Observation Improves Colorectal Polyp Visibility in Color Difference Value and an Endoscopist’s Visibility

et al. 2018

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Background/Aims: Settings of structure and color enhancement (CE) change view of white light imaging and a preset low enhancement setting is used regularly. The aim of this study was to investigate whether higher enhancement settings increased colorectal lesions’ visibility with endoscopists’ visibility scoring and objective color difference (CD) value. Methods: From April 2015 to September 2015, we analyzed 27 pictures and 100 videos of colorectal lesions. Combinations of structure enhancement (B3, A3, A5) and CE (CE 0, 1, 3) were evaluated and CD values of 2 corresponding modes (high enhancement: A5 + CE3, preset low enhancement: A3 + CE0) were calculated using marketed software. In the video, these 2 modes were evaluated. All pictures and movies were graded by 4 endoscopists using visibility scores: score 4 (excellent) to score 1 (poor). Results: The scores of A3 + CE0 (2.74 ± 1.09) were significantly lower than those of all other higher enhancement settings such as B3 + CE1 (3.11 ± 1.08), A3 + CE1 (3.33 ± 0.91), and A5 + CE3 (3.56 ± 0.74; p < 0.001). The CD value of A5 + CE3 was significantly higher than A3 + CE0 (20.2 ± 6.9 vs. 12.9 ± 5.6, p < 0.001). In the video, the scores for A5 + CE3 were significantly higher than A3 + CE0 (3.27 ± 0.83 vs. 2.53 ± 1.05, p < 0.001). Conclusions: Higher enhancement settings increased visibility of colorectal lesions.

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Section: Discussionmentioning

confidence: 79%

High Enhancement Settings for White Light Observation Improves Colorectal Polyp Visibility in Color Difference Value and an Endoscopist’s Visibility

et al. 2018

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“…As a result of analyzing the color tone, LCI distinguished colon mucosal white color compared to WLI, indicating the remissioncolon mucosa of UC with no inflammatory cell infiltration in ROI was easily detected by LCI. In the case of Mayo endoscopic subscore was 0, color difference could be recognized significantly more easily compared to Mayo endoscopic sub-score was [1][2][3]p = 0.02).…”

Section: Io4-5mentioning

confidence: 88%

“…Recent data have shown that it is useful for detection of colonic neoplasia, as well as characterization and differentiation of gastric and colonic neoplasia. In a multicentre RCT, it was shown that compared to white light imaging (WLI), BLI detected a significantly greater mean number of adenoma (WLI 1.01 ± 1.36, BLI 1.27 ± 1.73; P = 0.008) [1]. Another RCT demonstrated that BLI decreased adenoma miss rate compared to WLI (1.6% vs 10%, p = 0.001) [2].…”

Section: Tiing Leong Angmentioning

confidence: 99%

IGICS: JGA Keynote Program. The 10th International Gastrointestinal Consensus Symposium (IGICS). Gastrointestinal Cancer and Gastrointestinal Infection. February 10, 2018: Abstracts

2018

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“…New generation of BLI system (LASEREO, Fujifilm) includes a mixture of short-wavelength narrow-band light and white light. A novel multicentre prospective study found the mean number of polyps and adenoma detected per patient significantly higher when using LASEREO system compared to WLE [38].…”

Section: Introductionmentioning

confidence: 97%

Advances in endoscopic diagnosis of colorectal cancer

Čavlina¹,

Rustemović²

2017

Rad Hrvatske akademije znanosti i umjetnosti

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SummaryColorectal cancer (CRC) is the third most commonly diagnosed malignant tumor and the fourth leading cause of cancer death in the world. Since it is known that most of colorectal cancers arise from adenomatous polyps, screening programmes were developed in order to improve detection of polyps and early diagnosis of carcinoma. Colonoscopy is the gold standard for diagnosis of CRC. Because of its high adenoma missing rates and lower ability to differentiate between benign and malignant lesions novel techniques are being developed in order to improve mucosal visualization, reduce adenoma missing rates and enable in-vivo optical diagnosis. Methods can roughly be divided into three categories, ones that present improved visualization techniques (endoscopes with increased field of view, auxiliary imaging devices, so called addon devices), ones that enable more detail tissue characterization presenting the possibility for virtual biopsy (conventional or virtual chromoendoscopy, confocal laser endomicroscopy and endocytoscopy), and other minimally or non-invasive techniques.Further investigation is needed, but hopefully these innovations with continuous technical improvement might help to reduce the colorectal cancer incidence and mortality.

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Detectability of colorectal neoplastic lesions using a novel endoscopic system with blue laser imaging: a multicenter randomized controlled trial

Cited by 95 publications

References 44 publications

High Enhancement Settings for White Light Observation Improves Colorectal Polyp Visibility in Color Difference Value and an Endoscopist’s Visibility

High Enhancement Settings for White Light Observation Improves Colorectal Polyp Visibility in Color Difference Value and an Endoscopist’s Visibility

IGICS: JGA Keynote Program. The 10th International Gastrointestinal Consensus Symposium (IGICS). Gastrointestinal Cancer and Gastrointestinal Infection. February 10, 2018: Abstracts

Advances in endoscopic diagnosis of colorectal cancer

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