Detecting depression in Alzheimer?s disease: evaluation of four different scales

Müller‐Thomsen, Tomas; Arlt, Sönke; Mann, Ulrike; Maß, Reinhard; Ganzer, Stefanie

doi:10.1016/j.acn.2004.03.010

Cited by 150 publications

(136 citation statements)

References 17 publications

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“…In research studies, internal consistency, interrater reliability, and concurrent validity were shown to be acceptable, 31,78,162 and the CSDD was shown to have acceptable psychometric properties in severe dementia. 78 Sensitivity to change was demonstrated in a few trials.…”

Section: Depression In Non-pd Patientsmentioning

confidence: 99%

“…78 Sensitivity to change was demonstrated in a few trials. [163][164][165][166] Informed other ratings on the CSDD in patients with dementia were shown to have higher sensitivity for correctly diagnosing depression than other depression scales, including the BDI, the Ham-D, and the GDS (all modified for caregiver rating).…”

Section: Depression In Non-pd Patientsmentioning

confidence: 99%

“…30,76 Although it has been shown to be valid in older patients with mild cognitive impairment, 77 sparse data on patients with severe cognitive impairment exist. 78 The MADRS (see, for example, Table 3 located in Supplementary Materials) is in the public domain (although because of its publication in the British Journal of Psychiatry, the scale is formally copyrighted by this journal). It has been translated into several European and Asian languages.…”

Section: Montgomery-asberg Depression Rating Scale (Madrs) Depressionmentioning

confidence: 99%

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Depression rating scales in Parkinson's disease: Critique and recommendations

Schrag¹,

Barone²,

Brown³

et al. 2007

Movement Disorders

594

348

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Depression is a common comorbid condition in Parkinson's disease (PD) and a major contributor to poor quality of life and disability. However, depression can be difficult to assess in patients with PD due to overlapping symptoms and difficulties in the assessment of depression in cognitively impaired patients. As several rating scales have been used to assess depression in PD (dPD), the Movement Disorder Society commissioned a task force to assess their clinimetric properties and make clinical recommendations regarding their use. A systematic literature review was conducted to explore the use of depression scales in PD and determine which scales should be selected for this review. The scales reviewed were the Beck Depression Inventory (BDI), Hamilton Depression Scale (Ham-D), Hospital Anxiety and Depression Scale (HADS), Zung Self-Rating Depression Scale (SDS), Geriatric Depression Scale (GDS), Montgomery-Asberg Depression Rating Scale (MADRS), Unified Parkinson's Disease Rating Scale (UPDRS) Part I, Cornell Scale for the Assessment of Depression in Dementia (CSDD), and the Center for Epidemiologic Studies Depression Scale (CES-D). Seven clinical researchers with clinical and research experience in the assessment of dPD were assigned to review the scales using a structured format. The most appropriate scale is dependent on the clinical or research goal. However, observer-rated scales are preferred if the study or clinical situation permits. For screening purposes, the HAM-D, BDI, HADS, MADRS, and GDS are valid in dPD. The CES-D and CSDD are alternative instruments that need validation in dPD. For measurement of severity of depressive symptoms, the Ham-D, MADRS, BDI, and SDS scales are recommended. Further studies are needed to validate the CSDD, which could be particularly useful for the assessment of severity of dPD in patients with comorbid dementia. To account for overlapping motor and nonmotor symptoms of depression, adjusted instrument cutoff scores may be needed for dPD, and scales to assess severity of motor symptoms (e.g., UPDRS) should also be included to help adjust for confounding factors. The HADS and the GDS include limited motor symptom assessment and may, therefore, be most useful in rating depression severity across a range of PD severity; however, these scales appear insensitive in severe depression. The complex and time-consuming task of developing a new scale to measure depression specifically for patients with PD is currently not warranted.

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Section: Depression In Non-pd Patientsmentioning

confidence: 99%

Section: Depression In Non-pd Patientsmentioning

confidence: 99%

Section: Montgomery-asberg Depression Rating Scale (Madrs) Depressionmentioning

confidence: 99%

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Depression rating scales in Parkinson's disease: Critique and recommendations

Schrag¹,

Barone²,

Brown³

et al. 2007

Movement Disorders

594

348

View full text Add to dashboard Cite

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“…The Montgomery andÅsperg Depression Scale, the Cornell Scale for Depression in Dementia and the Nurses Observation Scale for Geriatric Patients are other possibilities to assess the depression levels in AD patients [51].…”

Section: Psychological Evaluationmentioning

confidence: 99%

“…As depression is one of the most frequent non-cognitive symptoms in AD (to the extent that a pathogenetic relation between depression and AD has been suggested [51]), psychological evaluation is mainly focused on depression symptoms' measurement.…”

Section: Psychological Evaluationmentioning

confidence: 99%