This study attempts to quantify the relative contributions of vegetation greening in China due to climatic and human influences from multiple observational datasets. Satellite measured vegetation greenness, Normalized Difference Vegetation Index (NDVI), and relevant climate, land cover, and socioeconomic data since 1982 are analyzed using a multiple linear regression (MLR) method. A statistically significant positive trend of average growing-season (April-October) NDVI is found over more than 34% of the vegetated areas, mainly in North China, while significant decreases in NDVI are only seen in less than 5% of the areas. The relationships between vegetation and climate (temperature, precipitation, and radiation) vary by geographical location and vegetation type. We estimate the NDVI changes in association with the non-climatic effects by removing the climatic effects from the original NDVI time series using the MLR analysis. Our results indicate that land use change is the dominant factor driving the long-term changes in vegetation greenness. The significant greening in North China is due to the increase in crops, grasslands, and forests. The socioeconomic datasets provide consistent and supportive results for the non-climatic effects at the provincial level that afforestation and reduced fire events generally have a major contribution. This study provides a basis for quantifying the non-climatic effects due to possible human influences on the vegetation greening in China.