This study aimed to investigate the application of machine learning techniques for disease prediction. Three popular machine learning algorithms, Random Forest, Support Vector Machines and Naive Bayes, were employed and their performance was evaluated. Results showed that the best performing model was based on Random Forest algorithm with the average accuracy of 87%. This model has been additionally tuned in order to achieve even better performance, which resulted with 90% accuracy. This study highlights the potential of AI in disease prediction and provides insights into the importance of algorithm selection and tuning for optimal performance.