Detection and identification of human parechoviruses from clinical specimens

Detection of human parechovirus (HPeV)-3 in spinal fluid specimens from pediatric patients in the Chicago area

“…picornaviridae.com/parechovirus/hpev/hpev.htm), but data about characteristics of infection caused by each HPeV type is still very limited. Recent studies have shown that HPeV1 was the type most frequently found in stool or respiratory samples, 1,8,[16][17][18][19][20][21] although the clinical significance of finding HPeV in these sites is not clear. By testing 421 CSF specimens, we identified HPeV3 in 10 patients.…”

Detection and characterization of human parechoviruses in archived cell cultures, in Hungary

“…HPeV4 was detected less frequently in previous studies. 10,16,17 Detection of highly identical HPeV4 strains may represent a cluster of symptomatic infection.…”

Human Parechoviruses, New Players in the Pathogenesis of Viral Meningitis

“…While EVs generally affect individuals of all ages, more than 90% of HPeV infections have been described in children younger than 5 years of age, (Abed & Boivin, 2006;Baumgarte et al, 2008;Benschop et al, 2008cBenschop et al, , 2010aChen et al, 2009;Grist et al, 1978;Khetsuriani et al, 2006aKhetsuriani et al, , 2006bPham et al, 2010;Tapia et al, 2008). WHO data from [1967][1968][1969][1970][1971][1972][1973][1974] reported that 94% of the HPeV1 infections were found in children < 4 years of age, of which 60% where < 1 year of age.…”