2002
DOI: 10.1109/10.979356
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Detection and measurement of retinal vessels in fundus images using amplitude modified second-order Gaussian filter

Abstract: In this paper, the fitness of estimating vessel profiles with Gaussian function is evaluated and an amplitude-modified second-order Gaussian filter is proposed for the detection and measurement of vessels. Mathematical analysis is given and supported by a simulation and experiments to demonstrate that the vessel width can be measured in linear relationship with the "spreading factor" of the matched filter when the magnitude coefficient of the filter is suitably assigned. The absolute value of vessel diameter c… Show more

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Cited by 264 publications
(119 citation statements)
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“…In Hoover's algorithm [20] a piece of the blood vessel network is hypothesized by probing an area of the matched-filter response image and, while doing so, the threshold on the matched filter is iteratively decreased. Gang et al [17] proposes an amplitude-modified second-order derivative of a Gaussian filter to detect vessels at scales that match their widths. Steerable filters are introduced in [14] and extended in [54].…”
Section: Introductionmentioning
confidence: 99%
“…In Hoover's algorithm [20] a piece of the blood vessel network is hypothesized by probing an area of the matched-filter response image and, while doing so, the threshold on the matched filter is iteratively decreased. Gang et al [17] proposes an amplitude-modified second-order derivative of a Gaussian filter to detect vessels at scales that match their widths. Steerable filters are introduced in [14] and extended in [54].…”
Section: Introductionmentioning
confidence: 99%
“…Edge-based methods attempt to identify vessel edges with edge detector, such as Sobel operator [5] and Canny's method [6], morphological detector [7], directional matched differentiator template [4].Kernel-based methods work by convolving images with a filter kernel defined by the model of vessel cross-sectional profile. Blurred half-elliptical profile [8], Gaussian shaped profile [7,9,10], and simple rectangular profile [11] have been proposed for modeling profile crosssections. Based on the idea of fingerprint minutiae [14,15], a robust pattern was first introduced in [2], where a set of landmarks (bifurcations and crossovers of retinal vessel tree) were extracted and used as feature points.…”
Section: Previous Workmentioning
confidence: 99%
“…The main cause of visual impairment and blindness in ROP is retinal detachment which is the subsequence of the scars in turn. Swollen and twisted veins contribute to Plus-disease (PD) that is considered as the most severe type of ROP [4]. In Figure 1, retinal detachment of scleral membrane due to the stretching of the wound contraction caused by abnormal blood vessel growth is shown.…”
Section: Introductionmentioning
confidence: 99%