Detection of a mammalian-like astrovirus in bird, European roller (Coracias garrulus)

Pankovics, Péter; Boros, Ákos; Kiss, Tamás; Delwart, Eric; Reuter, Gábor

doi:10.1016/j.meegid.2015.06.020

Cited by 31 publications

(22 citation statements)

References 41 publications

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“…Although AstVs are regarded as viruses with a robust host-species restriction, several pieces of evidences in mammals (including humans) indicate that the host species barrier may be permeable in some occasions, and that heterologous viruses may stably adapt to the new host (Finkbeiner et al, 2008(Finkbeiner et al, , 2009Nagai et al, 2015). Moreover, occasional transmission of AstVs is thought to have occurred between avian and mammalian species in both directions (Sun et al, 2014;Pankovics et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Genome analysis of canine astroviruses reveals genetic heterogeneity and suggests possible inter-species transmission

et al. 2017

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Canine astrovirus RNA was detected in the stools of 17/63 (26.9%) samples, using either a broadly reactive consensus RT-PCR for astroviruses or random RT-PCR coupled with massive deep sequencing. The complete or nearly complete genome sequence of five canine astroviruses was reconstructed that allowed mapping the genome organization and to investigate the genetic diversity of these viruses. The genome was about 6.6kb in length and contained three open reading frames (ORFs) flanked by a 5' UTR, and a 3' UTR plus a poly-A tail. ORF1a and ORF1b overlapped by 43 nucleotides while the ORF2 overlapped by 8 nucleotides with the 3' end of ORF1b. Upon genome comparison, four strains (HUN/2012/2, HUN/2012/6, HUN/2012/115, and HUN/2012/135) were more related genetically to each other and to UK canine astroviruses (88-96% nt identity), whilst strain HUN/2012/126 was more divergent (75-76% nt identity). In the ORF1b and ORF2, strains HUN/2012/2, HUN/2012/6, and HUN/2012/135 were related genetically to other canine astroviruses identified formerly in Europe and China, whereas strain HUN/2012/126 was related genetically to a divergent canine astrovirus strain, ITA/2010/Zoid. For one canine astrovirus, HUN/2012/8, only a 3.2kb portion of the genome, at the 3' end, could be determined. Interestingly, this strain possessed unique genetic signatures (including a longer ORF1b/ORF2 overlap and a longer 3'UTR) and it was divergent in both ORF1b and ORF2 from all other canine astroviruses, with the highest nucleotide sequence identity (68% and 63%, respectively) to a mink astrovirus, thus suggesting a possible event of interspecies transmission. The genetic heterogeneity of canine astroviruses may pose a challenge for the diagnostics and for future prophylaxis strategies.

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Section: Discussionmentioning

confidence: 99%

Genome analysis of canine astroviruses reveals genetic heterogeneity and suggests possible inter-species transmission

et al. 2017

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“…Unexpectedly there is no clear clustering of viruses separated by hosts of terrestrial or aquatic origins (Figure 1a,b). In addition to the classified MAstV species, there are numerous divergent viruses isolated from diverse species which likely represent new species awaiting formal classification (Figure 1a) [51]. …”

Section: Non-human Mastvmentioning

confidence: 99%

“…Fewer land dwelling wild birds have been found to harbor avian astroviruses including doves and pigeons (order Colombiformes), European roller (order Coraciiformes), and black-naped monarch (order Passeriformes) [51,104,110,111]. These viruses are highly divergent and largely unclassified, suggesting these viruses are endemic to the wild bird population (Figure 2a,b).…”

Section: Avastrovirusmentioning

confidence: 99%

“…There also appears to be transmission between avian and mammalian species. The highly divergent strains isolated from European roller (Er/SZAL6/HUN/2011 and Er/BMTK529/HUN/2011) exhibited low identity to avian and mammalian astroviruses, cluster within the MAstV lineage, and were likely derived from multiple recombination and interspecies transmission events [51]. The carnivorous diet of this avian species may have facilitated the interspecies transmission event between a rodent or small mammal species.…”

Section: Interspecies Transmissionmentioning

confidence: 99%

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The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses

Donato

Vijaykrishna

2017

Viruses

140

144

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Astroviruses are a diverse family of viruses that infect a wide range of mammalian and avian hosts. Here we describe the phylogenetic diversity and current classification methodology of astroviruses based on the ORF1b and ORF2 genes, highlighting the propensity of astroviruses to undergo interspecies transmission and genetic recombination which greatly increase diversity and complicate attempts at a unified and comprehensive classification strategy.

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“…They belong to the family of Astroviridae and are divided into two genera: Avastrovirus and Mamastrovirus. They infect birds and mammals, respectively, despite the association between host species and astV genus has been recently evidenced to be permeable (Pankovics et al, 2015). AstVs are distributed widely and some have been identified as a cause of gastroenteritis in humans and other mammals (Koci et al, 2000;Kurtz and Lee, 1987;Matsui and Herrmann, 2003).…”

Section: Introductionmentioning

confidence: 99%

Diversity of bat astroviruses in Lao PDR and Cambodia

Lacroix

Duong

Hul

et al. 2017

Infection, Genetics and Evolution

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Astroviruses are known to infect humans and a wide range of animal species, and can cause gastroenteritis in their hosts. Recent studies have reported astroviruses in bats in Europe and in several locations in China. We sampled 1876 bats from 17 genera at 45 sites from 14 and 13 provinces in Cambodia and Lao PDR respectively, and tested them for astroviruses. Our study revealed a high diversity of astroviruses among various Yangochiroptera and Yinpterochiroptera bats. Evidence for varying degrees of host restriction for astroviruses in bats was found. Furthermore, additional Pteropodid hosts were detected. The astroviruses formed distinct phylogenetic clusters within the genus Mamastrovirus, most closely related to other known bat astroviruses. The astrovirus sequences were found to be highly saturated indicating that phylogenetic relationships should be interpreted carefully. An astrovirus clustering in a group with other viruses from diverse hosts, including from ungulates and porcupines, was found in a Rousettus bat. These findings suggest that diverse astroviruses can be found in many species of mammals, including bats.

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Detection of a mammalian-like astrovirus in bird, European roller (Coracias garrulus)

Cited by 31 publications

References 41 publications

Genome analysis of canine astroviruses reveals genetic heterogeneity and suggests possible inter-species transmission

Genome analysis of canine astroviruses reveals genetic heterogeneity and suggests possible inter-species transmission

The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses

Diversity of bat astroviruses in Lao PDR and Cambodia

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