“…Anaphylaxis is an acute, serious, systemic allergic reaction related to a variety of triggers, mechanisms, clinical presentations, and grades of severity (1) . Several risk factors have been recognized for myocardial infarction (MI); however, the differential diagnosis of this condition in an anaphylactic patient is either an allergic acute coronary syndrome (ACS) known as Kounis syndrome or the effect of epinephrine treatment (2,3) . Kounis syndrome refers to the occurrence of ACS including coronary spasm, acute myocardial infarction, and stent thrombosis with mast cells and platelets activation in a patient experiencing hypersensitivity, allergy, or anaphylaxis (4) .…”