Detection of Hepatocellular Carcinoma: Comparison of Dynamic MR Imaging with Dynamic Double Arterial Phase Helical CT

Abstract

Dynamic MR imaging with 3D Fourier transformation-enhanced fast gradient-echo sequences with a special spectral inversion recovery pulse is recommended to improve the detection of hypervascular hepatocellular carcinoma nodules in addition to the use of dynamic helical CT with double arterial phase imaging.

Double-contrast magnetic resonance imaging of hepatocellular carcinoma after transarterial chemoembolization

“…However, it is known that well-differentiated HCs may contain Kupfer cells and show some uptake of SPIO. This lesions can be missed on SPIO technique [35].…”

“…Another potential limitation might be the fact that the enhancement pattern of the extracellular contrast medium could have been influenced by the prior administration of the SPIO. Although, SPIO affects the signal intensity of normal liver parenchyma on both T1-and T2-weighted images , this signal reduction does not influence the gadolinium enhancement and so the analysis of hypervascular areas is not affected [35].…”

CT versus MR Imaging of Hepatocellular Carcinoma: Toward Improved Treatment Decisions

“…1,4 In MDCT, progressively higher spatial and temporal resolutions have been achieved by increasing gantry rotation speed and number of detector rows. Advances in MDCT technology have enabled more precise evaluation of the hemodynamics of liver tumor and improved diagnostic accuracy.…”

“…Previously, we showed no signiˆcant diŠerence in sensitivity between dynamic MDCT and dynamic MR imaging for detecting hypervascular HCC. 4 We would consider cost and radiation exposure in choosing modalities, especially for follow-up studies in HCC.…”

“…Dynamic MR imaging with 3D T 1 -weighted gradient echo sequence and nonspeciˆc contrast medium, such as gadopentetate dimeglumine (Gd-DTPA), is also reported useful. 4 Moreover, the clinical availability of tissue-speciˆc MR contrast media that accumulate in KupŠer cells by phagocytosis or in hepatic cell by hepatocytic function are reported to improve tumor detactability. [5][6][7] The high diagnostic ability with use of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA), a contrast medium speciˆc to hepatic tissue, has made it essential in liver imaging.…”