Detection of Human Immunodeficiency Virus Antibodies in Oral Fluids

Hodinka, Richard L.; Nagashunmugam, Thandavarayan; Malamud, Daniel

doi:10.1128/cdli.5.4.419-426.1998

Cited by 103 publications

(46 citation statements)

References 65 publications

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“…These systems consist of a treated cotton pad or collection platform that is placed between the cheek and lower gum for two minutes. 4 The devices draw antibody-rich transudate from the oral mucosa that can be tested for HIV-1 antibodies. Rapid enzyme immunoassay HIV-1 tests can be performed accurately, at reasonable cost, and within the time frame (results within one hour) of a typical clinic visit in many public health settings.…”

mentioning

confidence: 99%

Education in HIV Risk Screening, Counseling, Testing, and Referral: Survey of U.S. Dental Schools

Patton

Santos²,

McKaig³

et al. 2002

Journal of Dental Education

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According to Centers for Disease Control and Prevention estimates, thousands of Americans are infected with HIV but are unaware of their infection status. National disease prevention goals to identify and treat these individuals will benefit from HIV risk screening, counseling, testing, and referral services conducted in nontraditional settings and the use of alternative diagnostic methods such as oral fluid‐based HIV antibody testing. Using a mail survey of the fifty‐four U.S. dental schools (85 percent response rate), this study assessed the teaching and practice of HIV risk screening, as well as the opinions of dental educators regarding HIV counseling and testing and a possible role for oral fluid‐based HIV antibody testing in dental offices. All responding dental schools have curriculum and clinical education training regarding HIV behavioral risks, medical history, and use of oral manifestations as indicators of HIV. Educators felt risk screening and referral for HIV counseling and testing was part of a dentist's professional role. One‐third of respondents indicated they might include HIV counseling and testing using a rapid oral fluid‐based HIV antibody test in their clinics. However, these respondents lacked confidence that graduating dentists have the skills and willingness to conduct HIV counseling and testing in dental practice. Lack of training in prevention counseling was seen as a primary barrier.

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mentioning

confidence: 99%

Education in HIV Risk Screening, Counseling, Testing, and Referral: Survey of U.S. Dental Schools

Patton

Santos²,

McKaig³

et al. 2002

Journal of Dental Education

View full text Add to dashboard Cite

show abstract

“…Biomarkers for the detection of diseases, such as caries, oral cancer and periodontal disease, as well as systemic disease such as hepatitis, Sjögren's syndrome, breast cancer, pancreatic cancer and HIV have been shown to be present in saliva. [44][45][46][47][48][49][50][51] Whole saliva can be obtained by either unstimulated or stimulated collection. Stimulated saliva collection is accomplished by masticatory or gustatory stimulation, for example, chewing on parafifin or…”

Section: Saliva As a Diagnostic Mediummentioning

confidence: 99%

Emerging horizons of salivary diagnostics for periodontal disease

2014

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The field of salivary diagnostics to allow risk determination for periodontal diseases is advancing. New technologies in proteomics, genomics and nanotechnologies have continued the discovery of discriminatory periodontal disease biomarkers. This review briefly overviews biomarker studies that have been completed in saliva for the detection of periodontal disease since 2010. Disease specific biomarkers could be used in risk determination, treatment planning and disease progression. Currently, diagnostic tests are commercially available, and the development of point-of-care tests is expanding. Even though challenges remain, salivary diagnostics for periodontal disease is promising and could facilitate the diagnostics and treatment in a clinical practice by dental practitioners.

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“…Almost anything one can measure in blood, one can measure in saliva. Saliva has been used reliably to detect HIV 1 and 2, as well as viral hepatitis A, B and C. 9,10 It also can be used to monitor a variety of drug levels, including those of marijuana, cocaine and alcohol. 1 Compelling reasons exist to use saliva as a diagnostic fluid.…”

Section: Saliva As a Diagnostic Fluidmentioning

confidence: 99%