Detection of Pesticides and Metabolites Using Surface-Enhanced Raman Spectroscopy (SERS): Acephate

Clauson, Susan L.; Sylvia, James M.; Arcury, Thomas A.; Summers, Phillip; Spencer, Kevin

doi:10.1366/14-07594

Cited by 29 publications

(14 citation statements)

References 51 publications

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“…In SERS, the laser examines an area of a microscopically roughened or "activated" gold or silver surface that has an attached surface plasmon. Thus, the vibrational modes of adsorbed analyte within the examined volume, which are involved with the surface interaction, are enhanced by factors of up to 10 9 , enabling trace detection [76].…”

Section: How To Detect Pesticides and Their Impact On Cellular Metabolism For Male Fertility Assessment?mentioning

confidence: 99%

Pesticides and Male Fertility: A Dangerous Crosstalk

et al. 2021

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In recent decades, an increasing incidence of male infertility has been reported. Interestingly, and considering that pesticides have been used for a long time, the high incidence of this pathological state is concomitant with the increasing use of these chemicals, suggesting they are contributors for the development of human infertility. Data from literature highlight the ability of certain pesticides and/or their metabolites to persist in the environment for long periods of time, as well as to bioaccumulate in the food chain, thus contributing for their chronic exposure. Furthermore, pesticides can act as endocrine disrupting chemicals (EDCs), interfering with the normal function of natural hormones (which are responsible for the regulation of the reproductive system), or even as obesogens, promoting obesity and associated comorbidities, like infertility. Several in vitro and in vivo studies have focused on the effects and possible mechanisms of action of these pesticides on the male reproductive system that cause sundry negative effects, even though through diverse mechanisms, but all may lead to infertility. In this review, we present an up-to-date overview and discussion of the effects, and the metabolic and molecular features of pesticides on somatic cells and germinal tissues that affect germ cell differentiation.

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Section: How To Detect Pesticides and Their Impact On Cellular Metabolism For Male Fertility Assessment?mentioning

confidence: 99%

Pesticides and Male Fertility: A Dangerous Crosstalk

et al. 2021

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“…For instance, APT, as a kind of organophosphorus pesticides, can effectively defense of chewing type and sucking pests and mites. On the other hand, it may cause poisoning symptoms include dizziness, nausea, vomiting, diarrhea and even coma and respiratory paralysis [ 33 ]. Therefore, it is necessary to apply SERS technology to detect pesticide residues in the real world.…”

Section: Resultsmentioning

confidence: 99%

Au-Decorated Dragonfly Wing Bioscaffold Arrays as Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Simultaneous Determination of Pesticide Residues

et al. 2018

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Rapid sampling and multicomponent analysis are vital in pesticide residue detection. In this work, we proposed a SERS platform to detect three kinds of pesticides on apple peels simultaneously by a straightforward “press and peel off” method. The flexible Au/dragonfly wing (Au/DW) substrate was obtained from sputtering Au nanoislands on DW bioscaffold arrays by a simple direct current (DC) magnetron sputtering system. The high-performance substrate exhibited a low limit of detection (LOD) to 4-aminothiophenol (4-ATP) (10−9 M), outstanding reproducibility (less than 12.15%), good stability and suitability in multifold pesticide residues detection. Considering its excellent sample collection efficiency, the Au/DW substrate was employed to solve critical pesticide residue problems for detection of acephate (APT), cypermethrin (CPT), tsumacide (MTMC) and their multiple components on apple peels. The results show that the LOD was 10−3 ng/cm2 for APT obtained on the apple surface with a calculation equation of y = 0.26x + 6.68 and a determination coefficient (R2) of 0.970. Additionally, the LOD values for CPT and MTMC were 10−3 ng/cm2 and 10−4 ng/cm2, respectively. The finding in this work may provide a promising biomimetic SERS platform for on-spot detection of other organic pollutants in the food industry and inenvironmental protection.

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“…151 The major vibrational bands for acephate are associated with the P-O-C, P-S-C, and ketone features. To determine the spectral overlap between acephate and urea, urea was detected on the same electrochemically roughed substrates.…”

Section: Metabolitesmentioning

confidence: 99%

“…It was also reported that acephate can be efficiently extracted from urine to remove the overwhelming urea interference to obtain ppb detection limits. 151 …”

Section: Metabolitesmentioning

confidence: 99%

Bioanalytical applications of surface-enhanced Raman spectroscopy: de novo molecular identification

Nguyen

Peters

Schultz

2017

Reviews in Analytical Chemistry

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Surface enhanced Raman scattering (SERS) has become a powerful technique for trace analysis of biomolecules. The use of SERS-tags has evolved into clinical diagnostics, the enhancement of the intrinsic signal of biomolecules on SERS active materials shows tremendous promise for the analysis of biomolecules and potential biomedical assays. The detection of the de novo signal from a wide range of biomolecules has been reported to date. In this review, we examine different classes of biomolecules for the signals observed and experimental details that enable their detection. In particular, we survey nucleic acids, amino acids, peptides, proteins, metabolites, and pathogens. The signals observed show that the interaction of the biomolecule with the enhancing nanostructure has a significant influence on the observed spectrum. Additional experiments demonstrate that internal standards can correct for intensity fluctuations and provide quantitative analysis. Experimental methods that control the interaction at the surface are providing for reproducible SERS signals. Results suggest that combining advances in methodology with the development of libraries for SERS spectra may enable the characterization of biomolecules complementary to other existing methods.

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Detection of Pesticides and Metabolites Using Surface-Enhanced Raman Spectroscopy (SERS): Acephate

Cited by 29 publications

References 51 publications

Pesticides and Male Fertility: A Dangerous Crosstalk

Pesticides and Male Fertility: A Dangerous Crosstalk

Au-Decorated Dragonfly Wing Bioscaffold Arrays as Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Simultaneous Determination of Pesticide Residues

Bioanalytical applications of surface-enhanced Raman spectroscopy: de novo molecular identification

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